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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Bill Monbouquette | 347.0 | 1953 | |
| 2 | Dennis Rasmussen | 307.0 | 1953 | |
| 3 | Stan Coveleski | 306.0 | 1953 | |
| 4 | Scott T Baker | 301.0 | 1953 | |
| 5 | Madison Bumgarner* | 295.0 | 1953 | |
| 6 | Dizzy Dean* | 293.0 | 1953 | |
| 6 | Lefty Williams | 293.0 | 1954 | |
| 8 | Greg Maddux* | 292.0 | 1954 | |
| 8 | Greg Maddux* | 292.0 | 1952 | |
| 8 | Greg Maddux* | 292.0 | 1953 | |
| 11 | Lefty Williams | 291.0 | 1953 | |
| 12 | Dizzy Dean* | 290.0 | 1954 | |
| 12 | Dizzy Dean* | 290.0 | 1946 | |
| 12 | Dizzy Dean* | 290.0 | 1947 | |
| 15 | Bill Monbouquette | 282.0 | 1954 | |
| 16 | Madison Bumgarner* | 281.0 | 1950 | |
| 16 | Dizzy Dean* | 281.0 | 1949 | |
| 18 | Dizzy Dean* | 280.0 | 1948 | |
| 18 | Hideo Nomo | 280.0 | 1953 | |
| 20 | Greg Mathews# | 278.0 | 1969 | |
| 20 | Larry Christenson | 278.0 | 1948 | |
| 22 | Schoolboy Rowe | 277.0 | 1947 | |
| 22 | Juan Pizarro | 277.0 | 1953 | |
| 24 | Dizzy Dean* | 276.0 | 1952 | |
| 25 | Dizzy Dean* | 275.0 | 1955 | |
| 26 | Mort Cooper | 274.0 | 1953 | |
| 26 | Hugh McQuillan | 274.0 | 1953 | |
| 26 | Pat Malone | 274.0 | 1949 | |
| 26 | Matt Moore | 274.0 | 1953 | |
| 30 | Bob Friend | 273.0 | 1949 | |
| 30 | Madison Bumgarner* | 273.0 | 1949 | |
| 30 | John D'Acquisto# | 273.0 | 1969 | |
| 30 | Greg Maddux* | 273.0 | 1950 | |
| 30 | Bill Monbouquette | 273.0 | 1955 | |
| 35 | Madison Bumgarner* | 272.0 | 1947 | |
| 35 | Stan Coveleski | 272.0 | 1952 | |
| 35 | Lefty Williams | 272.0 | 1948 | |
| 38 | Noah Syndergaard# | 271.0 | 1969 | |
| 38 | Mort Cooper | 271.0 | 1956 | |
| 38 | Schoolboy Rowe | 271.0 | 1949 | |
| 38 | Jon Lester | 271.0 | 1954 | |
| 38 | Brett Cecil | 271.0 | 1953 | |
| 43 | Mort Cooper | 270.0 | 1950 | |
| 43 | Bill C Lee | 270.0 | 1946 | |
| 43 | Bill Monbouquette | 270.0 | 1946 | |
| 46 | Bob Friend | 269.0 | 1946 | |
| 46 | Bob Friend | 269.0 | 1948 | |
| 48 | Gary Peters | 268.0 | 1947 | |
| 49 | Schoolboy Rowe | 267.0 | 1946 | |
| 49 | Hod Eller | 267.0 | 1949 | |
| 49 | Larry Christenson | 267.0 | 1947 | |
| 52 | Mat Latos# | 266.0 | 1969 | |
| 52 | Alex Fernandez | 266.0 | 1952 | |
| 52 | James Paxton# | 266.0 | 1968 | |
| 52 | Stan Coveleski | 266.0 | 1946 | |
| 56 | Schoolboy Rowe | 265.0 | 1950 | |
| 56 | Lefty Williams | 265.0 | 1950 | |
| 56 | Madison Bumgarner* | 265.0 | 1946 | |
| 56 | Alex Fernandez | 265.0 | 1954 | |
| 56 | Phil Hughes | 265.0 | 1946 | |
| 56 | Gary Peters | 265.0 | 1946 | |
| 56 | Madison Bumgarner* | 265.0 | 1948 | |
| 56 | Pat Malone | 265.0 | 1948 | |
| 64 | Frank Viola | 264.0 | 1950 | |
| 64 | Bill Wight | 264.0 | 1949 | |
| 64 | John Lackey# | 264.0 | 1968 | |
| 64 | Greg Maddux* | 264.0 | 1947 | |
| 68 | Gary Peters | 263.0 | 1948 | |
| 68 | Alex Fernandez | 263.0 | 1946 | |
| 68 | Hideo Nomo | 263.0 | 1955 | |
| 68 | Juan Marichal | 263.0 | 1946 | |
| 68 | Stan Coveleski | 263.0 | 1954 | |
| 68 | Frank Viola | 263.0 | 1947 | |
| 68 | James Shields | 263.0 | 1949 | |
| 68 | James Shields | 263.0 | 1953 | |
| 68 | Hod Eller | 263.0 | 1946 | |
| 77 | Frank Viola | 262.0 | 1954 | |
| 77 | Hiroki Kuroda | 262.0 | 1954 | |
| 77 | Dillon Gee | 262.0 | 1954 | |
| 77 | Hideo Nomo | 262.0 | 1954 | |
| 77 | Mort Cooper | 262.0 | 1949 | |
| 77 | Mort Cooper | 262.0 | 1952 | |
| 83 | Lefty Williams | 261.0 | 1949 | |
| 83 | Len Barker | 261.0 | 1948 | |
| 83 | Chien-Ming Wang | 261.0 | 1950 | |
| 83 | Bill Monbouquette | 261.0 | 1950 | |
| 83 | Tom Glavine | 261.0 | 1950 | |
| 88 | Tom Glavine | 260.0 | 1947 | |
| 88 | Johnny Babich | 260.0 | 1948 | |
| 88 | Phil Hughes | 260.0 | 1947 | |
| 88 | Stan Coveleski | 260.0 | 1955 | |
| 88 | Madison Bumgarner* | 260.0 | 1951 | |
| 88 | Lefty Williams | 260.0 | 1947 | |
| 94 | Greg Maddux* | 259.0 | 1955 | |
| 94 | Mort Cooper | 259.0 | 1947 | |
| 94 | Brett Cecil | 259.0 | 1952 | |
| 94 | Hideo Nomo | 259.0 | 1949 | |
| 94 | Schoolboy Rowe | 259.0 | 1948 | |
| 99 | Bill Monbouquette | 258.0 | 1949 | |
| 99 | Atley Donald | 258.0 | 1946 |
