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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Brett Cecil | 4307.1 | 1950-1969 | |
| 2 | Madison Bumgarner* | 4136.0 | 1946-1962 | |
| 3 | Dizzy Dean* | 3947.1 | 1946-1961 | |
| 4 | Frank Viola | 3806.2 | 1946-1961 | |
| 5 | Jon Lester | 3510.0 | 1947-1966 | |
| 6 | Mike Bruhert | 3383.1 | 1951-1968 | |
| 7 | Bob Osborn | 3335.0 | 1947-1964 | |
| 8 | Charlie Root | 3261.1 | 1951-1967 | |
| 9 | Hideo Nomo | 3090.0 | 1948-1961 | |
| 9 | Lefty Williams | 3090.0 | 1946-1959 | |
| 11 | Stan Coveleski | 3071.0 | 1946-1959 | |
| 12 | Dillon Gee | 2986.2 | 1950-1966 | |
| 13 | Matt Clement | 2984.2 | 1946-1959 | |
| 14 | Greg Maddux* | 2975.1 | 1946-1957 | |
| 15 | Ownie Carroll | 2925.1 | 1948-1963 | |
| 16 | Lary Sorensen# | 2900.2 | 1956-1969 | |
| 17 | Danny Darwin | 2864.0 | 1947-1962 | |
| 18 | Mort Cooper | 2783.1 | 1946-1958 | |
| 19 | James Shields | 2745.0 | 1946-1958 | |
| 20 | Schoolboy Rowe | 2741.1 | 1946-1958 | |
| 21 | Roger Craig | 2731.2 | 1950-1963 | |
| 22 | Scott Bankhead | 2694.0 | 1953-1967 | |
| 23 | Bill Monbouquette | 2692.0 | 1946-1956 | |
| 24 | Larry Christenson | 2630.1 | 1946-1961 | |
| 25 | Ed Lynch | 2615.2 | 1948-1962 | |
| 26 | James Paxton# | 2572.0 | 1957-1969 | |
| 27 | Steve D Barber | 2563.0 | 1953-1968 | |
| 28 | Francisco Cordova# | 2548.2 | 1955-1969 | |
| 29 | Don Schwall | 2548.0 | 1946-1959 | |
| 30 | Juan Pizarro | 2546.1 | 1946-1963 | |
| 31 | Jack Hallett | 2520.2 | 1955-1969 | |
| 32 | Freddy Garcia# | 2478.0 | 1956-1969 | |
| 33 | Don Robinson | 2466.0 | 1947-1961 | |
| 34 | Tim Stauffer# | 2465.2 | 1956-1969 | |
| 35 | Alex Fernandez | 2458.2 | 1946-1956 | |
| 36 | Scott T Baker | 2457.2 | 1946-1957 | |
| 37 | Corey Kluber | 2424.0 | 1948-1961 | |
| 38 | Matt Moore | 2393.2 | 1946-1958 | |
| 39 | Pat Malone | 2351.0 | 1948-1960 | |
| 40 | Toby Borland | 2278.0 | 1955-1969 | |
| 41 | Arthur Rhodes | 2275.1 | 1949-1963 | |
| 42 | Randy O'Neal | 2273.1 | 1952-1965 | |
| 43 | Bill C Lee | 2265.2 | 1946-1956 | |
| 44 | Yu Darvish | 2238.0 | 1950-1962 | |
| 45 | John Thomson | 2220.2 | 1946-1957 | |
| 46 | Kent Peterson# | 2219.1 | 1956-1969 | |
| 47 | Osiris Matos | 2215.0 | 1954-1967 | |
| 48 | Dennis Rasmussen | 2192.1 | 1950-1965 | |
| 49 | Bob Friend | 2145.1 | 1946-1957 | |
| 50 | Dutch Ulrich | 2125.2 | 1954-1965 | |
| 51 | Mark Mulder | 2120.1 | 1950-1961 | |
| 52 | Hugh McQuillan | 2118.1 | 1946-1956 | |
| 53 | John Lackey# | 2114.0 | 1960-1969 | |
| 54 | Shawn Estes# | 2103.2 | 1959-1969 | |
| 55 | Clay Buchholz# | 2102.2 | 1959-1969 | |
| 56 | Ralph Birkofer# | 2058.1 | 1956-1969 | |
| 57 | Gio Gonzalez | 2056.0 | 1954-1967 | |
| 58 | A J Griffin | 2016.1 | 1949-1961 | |
| 58 | Edinson Volquez | 2016.1 | 1953-1966 | |
| 60 | Ken Holtzman | 2012.1 | 1946-1960 | |
| 61 | Shelby Miller | 2009.1 | 1953-1966 | |
| 62 | Jim Kaat# | 2000.2 | 1954-1969 | |
| 63 | Johnny Welch | 1997.1 | 1946-1957 | |
| 64 | Mark Gubicza | 1985.0 | 1947-1960 | |
| 65 | David Palmer# | 1984.2 | 1955-1969 | |
| 66 | Kenta Maeda# | 1941.1 | 1959-1969 | |
| 67 | Phil Collins# | 1927.1 | 1956-1969 | |
| 68 | Brad Peacock | 1903.0 | 1955-1967 | |
| 69 | Bob Sebra# | 1893.2 | 1959-1969 | |
| 70 | Vincent Velasquez | 1852.1 | 1954-1969 | |
| 71 | Mike Smithson# | 1818.0 | 1961-1969 | |
| 72 | Jimmie Keenan# | 1817.1 | 1960-1969 | |
| 73 | Hod Eller | 1797.2 | 1946-1958 | |
| 74 | Don Kaiser | 1795.0 | 1950-1964 | |
| 75 | Chan Ho Park | 1765.1 | 1949-1966 | |
| 76 | Milt Gaston# | 1764.2 | 1960-1968 | |
| 77 | Erasmo E Ramirez | 1760.0 | 1946-1956 | |
| 78 | Kevin Slowey | 1759.1 | 1952-1961 | |
| 79 | Len Barker | 1750.2 | 1946-1955 | |
| 80 | Sam Militello | 1728.2 | 1956-1967 | |
| 81 | Aaron Harang# | 1727.0 | 1957-1969 | |
| 82 | Tom Glavine | 1720.0 | 1946-1952 | |
| 83 | John D'Acquisto# | 1719.1 | 1961-1969 | |
| 84 | Juan Marichal | 1716.2 | 1946-1956 | |
| 85 | Livan Hernandez | 1707.1 | 1946-1956 | |
| 86 | Jae Weong Seo# | 1704.0 | 1962-1969 | |
| 87 | Sean Newcomb | 1701.0 | 1953-1966 | |
| 88 | Joe Mays | 1700.0 | 1948-1957 | |
| 89 | Jameson Taillon | 1688.0 | 1950-1958 | |
| 90 | Gary Peters | 1685.1 | 1946-1958 | |
| 91 | George Murray | 1680.0 | 1952-1961 | |
| 92 | Glendon Rusch# | 1657.2 | 1961-1969 | |
| 93 | Bo Belinsky | 1633.1 | 1949-1964 | |
| 94 | Phil Hughes | 1620.1 | 1946-1955 | |
| 95 | Kirk McCaskill# | 1613.2 | 1961-1969 | |
| 96 | Hiroki Kuroda | 1608.2 | 1950-1958 | |
| 97 | Robbie Erlin | 1585.2 | 1947-1957 | |
| 98 | Al McBean# | 1576.1 | 1962-1969 | |
| 99 | Anthony DeSclafani | 1576.0 | 1948-1962 | |
| 100 | Erv Brame | 1569.0 | 1946-1955 |
