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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | G | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jason Marquis | 929 | 1952-1968 | |
| 2 | Derek Lowe | 826 | 1950-1967 | |
| 3 | Chris Sale# | 803 | 1955-1969 | |
| 4 | Mickey Storey# | 756 | 1955-1969 | |
| 5 | Darren Holmes# | 728 | 1957-1969 | |
| 6 | Reggie Cleveland | 705 | 1948-1966 | |
| 7 | Cory Burns | 702 | 1953-1967 | |
| 8 | Billy Wagner | 685 | 1946-1962 | |
| 9 | Kelvin Herrera | 677 | 1952-1968 | |
| 10 | Dave Von Ohlen | 668 | 1947-1960 | |
| 11 | Robert Coello | 662 | 1950-1966 | |
| 12 | Duane Ward | 651 | 1946-1959 | |
| 13 | Mike Henneman | 642 | 1951-1962 | |
| 14 | Fred Howard# | 639 | 1953-1969 | |
| 15 | Ken Giles | 638 | 1946-1959 | |
| 16 | Jesse Chavez | 631 | 1953-1968 | |
| 17 | Doug Jones | 628 | 1953-1969 | |
| 18 | Cam Bedrosian# | 609 | 1953-1969 | |
| 19 | Brett Cecil | 600 | 1950-1969 | |
| 19 | Tim Mayza | 600 | 1950-1964 | |
| 21 | Mike J Adams# | 570 | 1957-1968 | |
| 22 | Bob Osborn | 569 | 1947-1964 | |
| 23 | Drew Storen | 566 | 1950-1966 | |
| 24 | Harry Kelley | 561 | 1949-1965 | |
| 25 | Craig Kimbrel# | 559 | 1959-1969 | |
| 26 | Tom Butters# | 553 | 1958-1969 | |
| 27 | Steve Cishek# | 551 | 1957-1969 | |
| 28 | Tom Acker | 550 | 1949-1962 | |
| 28 | Andrew Bailey | 550 | 1955-1966 | |
| 30 | Don Hankins | 544 | 1953-1967 | |
| 31 | Madison Bumgarner* | 537 | 1946-1962 | |
| 32 | Keith Foulke | 519 | 1948-1961 | |
| 33 | Wilton Lopez | 517 | 1957-1969 | |
| 34 | Danny Darwin | 512 | 1947-1962 | |
| 34 | Jon Lester | 512 | 1947-1966 | |
| 34 | Bob McClure | 512 | 1946-1958 | |
| 37 | Mike Bruhert | 505 | 1951-1968 | |
| 38 | Toby Borland | 501 | 1955-1969 | |
| 39 | Dizzy Dean* | 499 | 1946-1961 | |
| 40 | Will Ohman | 497 | 1952-1965 | |
| 40 | Frank Viola | 497 | 1946-1961 | |
| 42 | German Gonzalez | 496 | 1954-1967 | |
| 43 | Chris C Hatcher# | 494 | 1959-1969 | |
| 43 | Carlos Marmol | 494 | 1946-1957 | |
| 45 | Jason Frasor | 493 | 1953-1965 | |
| 46 | Herb Bradley | 491 | 1956-1967 | |
| 47 | Tim Stoddard# | 489 | 1958-1969 | |
| 48 | Charlie Root | 486 | 1951-1967 | |
| 49 | David Palmer# | 481 | 1955-1969 | |
| 50 | Don Welchel | 480 | 1954-1966 | |
| 51 | Warren Brusstar# | 471 | 1961-1969 | |
| 52 | Tom Tellmann | 458 | 1955-1964 | |
| 53 | B J Ryan# | 456 | 1959-1969 | |
| 54 | Ricky Bottalico# | 453 | 1960-1969 | |
| 54 | Ownie Carroll | 453 | 1948-1963 | |
| 56 | Michael Feliz | 452 | 1949-1963 | |
| 56 | Chan Ho Park | 452 | 1949-1966 | |
| 58 | Juan Pizarro | 451 | 1946-1963 | |
| 58 | Henry Rodriguez | 451 | 1950-1963 | |
| 60 | Chad Bradford | 449 | 1951-1964 | |
| 61 | Steve Shea | 446 | 1958-1969 | |
| 62 | Stan Thomas# | 445 | 1958-1969 | |
| 63 | Jose R Alvarez | 444 | 1946-1956 | |
| 64 | Scott Bankhead | 438 | 1953-1967 | |
| 65 | Hideo Nomo | 437 | 1948-1961 | |
| 66 | Brian Wilson | 436 | 1951-1964 | |
| 67 | Ralph Birkofer# | 434 | 1956-1969 | |
| 68 | Dillon Gee | 430 | 1950-1966 | |
| 68 | Camilo Pascual# | 430 | 1950-1968 | |
| 70 | Lary Sorensen# | 428 | 1956-1969 | |
| 71 | Lester Oliveros | 427 | 1950-1965 | |
| 72 | George Kontos# | 426 | 1962-1969 | |
| 73 | Steve D Barber | 422 | 1953-1968 | |
| 73 | Joe Rogalski | 422 | 1951-1963 | |
| 75 | Matt Clement | 418 | 1946-1959 | |
| 76 | Freddy Garcia# | 417 | 1956-1969 | |
| 77 | Johnny Humphries | 416 | 1949-1960 | |
| 77 | Kent Peterson# | 416 | 1956-1969 | |
| 79 | Francisco Cordova# | 411 | 1955-1969 | |
| 80 | Dave Heaverlo | 409 | 1956-1968 | |
| 80 | Michael Wuertz | 409 | 1958-1969 | |
| 82 | Clint Brown | 406 | 1953-1964 | |
| 83 | Stan Coveleski | 405 | 1946-1959 | |
| 84 | Ed Whitson# | 404 | 1959-1969 | |
| 85 | Scott Atchison# | 403 | 1960-1969 | |
| 85 | Roger Craig | 403 | 1950-1963 | |
| 87 | Dale Mohorcic | 402 | 1952-1962 | |
| 88 | Greg Maddux* | 401 | 1946-1957 | |
| 88 | Justin Wilson | 401 | 1946-1955 | |
| 90 | Dick Hyde | 400 | 1950-1961 | |
| 90 | Mike Parrott | 400 | 1947-1960 | |
| 92 | Ed Lynch | 399 | 1948-1962 | |
| 92 | Don Schwall | 399 | 1946-1959 | |
| 94 | Jack Hallett | 398 | 1955-1969 | |
| 94 | Osiris Matos | 398 | 1954-1967 | |
| 94 | Alexander Torres | 398 | 1946-1958 | |
| 97 | Lefty Williams | 396 | 1946-1959 | |
| 98 | Mark Brandenburg# | 395 | 1958-1968 | |
| 99 | Fautino De Los Santos# | 393 | 1962-1969 | |
| 100 | Dennis Rasmussen | 392 | 1950-1965 |
