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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | W | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Madison Bumgarner* | 290 | 1946-1962 | |
| 2 | Brett Cecil | 263 | 1950-1969 | |
| 3 | Dizzy Dean* | 257 | 1946-1961 | |
| 4 | Charlie Root | 238 | 1951-1967 | |
| 5 | Mike Bruhert | 229 | 1951-1968 | |
| 6 | Frank Viola | 218 | 1946-1961 | |
| 7 | Jon Lester | 204 | 1947-1966 | |
| 8 | Danny Darwin | 192 | 1947-1962 | |
| 9 | Bob Osborn | 184 | 1947-1964 | |
| 10 | Greg Maddux* | 183 | 1946-1957 | |
| 11 | Matt Clement | 181 | 1946-1959 | |
| 11 | Stan Coveleski | 181 | 1946-1959 | |
| 13 | Ownie Carroll | 179 | 1948-1963 | |
| 14 | Scott Bankhead | 178 | 1953-1967 | |
| 14 | James Paxton# | 178 | 1957-1969 | |
| 16 | Francisco Cordova# | 177 | 1955-1969 | |
| 17 | Hideo Nomo | 174 | 1948-1961 | |
| 18 | Schoolboy Rowe | 172 | 1946-1958 | |
| 18 | Lefty Williams | 172 | 1946-1959 | |
| 20 | Dillon Gee | 166 | 1950-1966 | |
| 21 | Pat Malone | 164 | 1948-1960 | |
| 21 | Matt Moore | 164 | 1946-1958 | |
| 23 | Mort Cooper | 162 | 1946-1958 | |
| 23 | Bill Monbouquette | 162 | 1946-1956 | |
| 23 | Lary Sorensen# | 162 | 1956-1969 | |
| 26 | Jack Hallett | 156 | 1955-1969 | |
| 26 | Ed Lynch | 156 | 1948-1962 | |
| 28 | James Shields | 154 | 1946-1958 | |
| 29 | Freddy Garcia# | 153 | 1956-1969 | |
| 30 | Juan Pizarro | 151 | 1946-1963 | |
| 31 | Corey Kluber | 150 | 1948-1961 | |
| 31 | Osiris Matos | 150 | 1954-1967 | |
| 33 | Steve D Barber | 149 | 1953-1968 | |
| 34 | Roger Craig | 145 | 1950-1963 | |
| 35 | Scott T Baker | 143 | 1946-1957 | |
| 36 | Jimmie Keenan# | 142 | 1960-1969 | |
| 36 | Kent Peterson# | 142 | 1956-1969 | |
| 38 | Alex Fernandez | 140 | 1946-1956 | |
| 39 | Don Schwall | 139 | 1946-1959 | |
| 40 | Toby Borland | 136 | 1955-1969 | |
| 40 | Bob Sebra# | 136 | 1959-1969 | |
| 40 | Tim Stauffer# | 136 | 1956-1969 | |
| 40 | John Thomson | 136 | 1946-1957 | |
| 44 | Randy O'Neal | 134 | 1952-1965 | |
| 45 | Don Robinson | 131 | 1947-1961 | |
| 46 | Yu Darvish | 130 | 1950-1962 | |
| 47 | Larry Christenson | 128 | 1946-1961 | |
| 48 | Ralph Birkofer# | 127 | 1956-1969 | |
| 48 | John Lackey# | 127 | 1960-1969 | |
| 48 | Dutch Ulrich | 127 | 1954-1965 | |
| 51 | Clay Buchholz# | 125 | 1959-1969 | |
| 51 | John D'Acquisto# | 125 | 1961-1969 | |
| 51 | Bob Friend | 125 | 1946-1957 | |
| 54 | Bill C Lee | 124 | 1946-1956 | |
| 55 | Shawn Estes# | 123 | 1959-1969 | |
| 55 | Kenta Maeda# | 123 | 1959-1969 | |
| 57 | Mark Gubicza | 121 | 1947-1960 | |
| 58 | Jim Kaat# | 118 | 1954-1969 | |
| 59 | Mark Mulder | 117 | 1950-1961 | |
| 59 | Chris Sale# | 117 | 1955-1969 | |
| 61 | Shelby Miller | 115 | 1953-1966 | |
| 61 | Jameson Taillon | 115 | 1950-1958 | |
| 63 | Phil Collins# | 114 | 1956-1969 | |
| 63 | Jim Hickey# | 114 | 1957-1969 | |
| 65 | Johnny Welch | 113 | 1946-1957 | |
| 66 | Al McBean# | 112 | 1962-1969 | |
| 67 | Gio Gonzalez | 111 | 1954-1967 | |
| 68 | Erasmo E Ramirez | 110 | 1946-1956 | |
| 69 | Tom Glavine | 108 | 1946-1952 | |
| 70 | Kirk McCaskill# | 105 | 1961-1969 | |
| 70 | Sam Militello | 105 | 1956-1967 | |
| 70 | Arthur Rhodes | 105 | 1949-1963 | |
| 73 | Paxton Crawford# | 104 | 1961-1969 | |
| 73 | Brad Peacock | 104 | 1955-1967 | |
| 75 | Robbie Erlin | 103 | 1947-1957 | |
| 75 | Livan Hernandez | 103 | 1946-1956 | |
| 75 | David Palmer# | 103 | 1955-1969 | |
| 75 | Al Shealy# | 103 | 1962-1969 | |
| 79 | George Murray | 100 | 1952-1961 | |
| 79 | Dennis Rasmussen | 100 | 1950-1965 | |
| 81 | Hugh McQuillan | 99 | 1946-1956 | |
| 81 | Glendon Rusch# | 99 | 1961-1969 | |
| 81 | Jae Weong Seo# | 99 | 1962-1969 | |
| 84 | Kevin Slowey | 98 | 1952-1961 | |
| 85 | Bo Belinsky | 97 | 1949-1964 | |
| 85 | Juan Marichal | 97 | 1946-1956 | |
| 87 | Darren Holmes# | 96 | 1957-1969 | |
| 87 | Phil Hughes | 96 | 1946-1955 | |
| 89 | Vincent Velasquez | 95 | 1954-1969 | |
| 90 | Hod Eller | 94 | 1946-1958 | |
| 90 | Brad Penny# | 94 | 1963-1969 | |
| 90 | Gary Peters | 94 | 1946-1958 | |
| 93 | A J Griffin | 93 | 1949-1961 | |
| 94 | Milt Gaston# | 92 | 1960-1968 | |
| 94 | Derek Lowe | 92 | 1950-1967 | |
| 96 | Ken Holtzman | 91 | 1946-1960 | |
| 96 | Hiroki Kuroda | 91 | 1950-1958 | |
| 98 | Len Barker | 90 | 1946-1955 | |
| 99 | Joe Mays | 89 | 1948-1957 | |
| 99 | Sean Newcomb | 89 | 1953-1966 |
