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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Vern Kennedy | 292.0 | 1988 | |
| 2 | Dixie Leverett | 290.0 | 1986 | |
| 3 | Sloppy Thurston | 282.0 | 1985 | |
| 4 | Vern Kennedy | 279.0 | 1989 | |
| 5 | Vern Kennedy | 278.0 | 1984 | |
| 6 | Jeff Samardzija | 276.0 | 1984 | |
| 7 | Dillon Gee# | 275.0 | 1992 | |
| 8 | Britt Burns | 273.0 | 1992 | |
| 9 | Sam Jones# | 271.0 | 1992 | |
| 10 | Francisco Barrios | 270.0 | 1989 | |
| 11 | Charlie Wagner# | 260.0 | 1998 | |
| 12 | Bruce Howard# | 256.0 | 1989 | |
| 13 | Bob Harris | 255.0 | 1992 | |
| 14 | Bill Butler | 254.0 | 1991 | |
| 15 | Len Barker | 252.0 | 1994 | |
| 16 | Shawn Estes | 251.0 | 1989 | |
| 17 | Rollie Sheldon | 248.0 | 1996 | |
| 18 | Mike LaCoss | 247.0 | 1997 | |
| 19 | Bob Moose | 246.0 | 1991 | |
| 19 | Jakob Junis | 246.0 | 1996 | |
| 19 | John Burkett | 246.0 | 1990 | |
| 22 | Mark Lemongello | 244.0 | 1996 | |
| 23 | Francisco Barrios | 243.0 | 1985 | |
| 23 | Charlie Wagner# | 243.0 | 1999 | |
| 23 | Terry Mulholland | 243.0 | 1988 | |
| 26 | Scott McGregor | 242.0 | 1994 | |
| 27 | Mark Lemongello | 240.0 | 1983 | |
| 27 | Jim Hughes# | 240.0 | 1995 | |
| 29 | Charlie Wagner# | 239.0 | 1997 | |
| 29 | Jose Rijo# | 239.0 | 1992 | |
| 29 | Shawn Estes | 239.0 | 1987 | |
| 29 | Chris George# | 239.0 | 1998 | |
| 33 | Tyler Chatwood# | 238.0 | 1988 | |
| 33 | Jeff Suppan# | 238.0 | 1993 | |
| 33 | Thornton Lee | 238.0 | 1997 | |
| 36 | Fred Baczewski# | 237.0 | 1995 | |
| 36 | Bob Humphreys | 237.0 | 1992 | |
| 36 | Bob Knepper | 237.0 | 1992 | |
| 39 | Tyler Anderson | 236.0 | 1988 | |
| 40 | Len Barker | 234.0 | 1995 | |
| 40 | Kyle Gibson# | 234.0 | 1998 | |
| 40 | Cotton Pippen | 234.0 | 1992 | |
| 40 | Ismael Valdez | 234.0 | 1994 | |
| 44 | Homer Bailey# | 232.0 | 1990 | |
| 44 | Jeff Karstens# | 232.0 | 1996 | |
| 46 | Les Tietje | 231.0 | 1990 | |
| 46 | Brian Givens | 231.0 | 1992 | |
| 46 | Chuck Dobson | 231.0 | 1992 | |
| 46 | Albie Lopez | 231.0 | 1988 | |
| 46 | Bill Lee | 231.0 | 1983 | |
| 46 | Jack Russell | 231.0 | 1989 | |
| 52 | John Koronka | 230.0 | 1996 | |
| 52 | Shawn Estes | 230.0 | 1988 | |
| 52 | Jim Maloney# | 230.0 | 1991 | |
| 55 | Steve McCatty# | 229.0 | 1996 | |
| 55 | Ken Chase# | 229.0 | 1996 | |
| 55 | Hector Noesi# | 229.0 | 1994 | |
| 55 | Ted Gray | 229.0 | 1984 | |
| 55 | Walt Terrell | 229.0 | 1994 | |
| 60 | Jim Maloney# | 228.0 | 1986 | |
| 60 | John Koronka | 228.0 | 1995 | |
| 62 | Kevin Millwood# | 227.0 | 2001 | |
| 62 | Dixie Leverett | 227.0 | 1987 | |
| 62 | Francisco Barrios | 227.0 | 1992 | |
| 65 | Marv Breuer# | 226.0 | 1997 | |
| 65 | Dave Goltz# | 226.0 | 1999 | |
| 67 | Sloppy Thurston | 225.0 | 1999 | |
| 67 | John Burkett | 225.0 | 1987 | |
| 67 | Tyler Chatwood# | 225.0 | 1996 | |
| 67 | Marv Breuer# | 225.0 | 1998 | |
| 67 | Jesse Jefferson# | 225.0 | 1995 | |
| 67 | Al Javery | 225.0 | 1989 | |
| 73 | Len Barker | 224.0 | 1993 | |
| 73 | Thornton Lee | 224.0 | 1994 | |
| 73 | Jesse Jefferson# | 224.0 | 1997 | |
| 76 | Thornton Lee | 223.0 | 1999 | |
| 76 | Marv Breuer# | 223.0 | 1999 | |
| 76 | Marv Breuer# | 223.0 | 1996 | |
| 76 | Thornton Lee | 223.0 | 1995 | |
| 76 | Ben Sheets | 223.0 | 1982 | |
| 81 | Boots Poffenberger# | 222.0 | 1999 | |
| 81 | La Marr Hoyt# | 222.0 | 2001 | |
| 81 | Vern Kennedy | 222.0 | 1983 | |
| 84 | Sean West | 221.0 | 1995 | |
| 84 | Bob Forsch# | 221.0 | 1999 | |
| 84 | Kyle Gibson# | 221.0 | 1995 | |
| 84 | John Koronka | 221.0 | 1993 | |
| 84 | Luke Walker | 221.0 | 1995 | |
| 84 | Rufe Gentry# | 221.0 | 1997 | |
| 84 | Jim Maloney# | 221.0 | 1987 | |
| 84 | Thornton Lee | 221.0 | 1996 | |
| 84 | Chuck Dobson | 221.0 | 1988 | |
| 84 | Mike Bruhert | 221.0 | 1993 | |
| 94 | Ted Lyons | 220.0 | 1989 | |
| 94 | Steve Kraly | 220.0 | 1992 | |
| 94 | Ken Chase# | 220.0 | 1999 | |
| 94 | Jeff Karstens# | 220.0 | 1999 | |
| 94 | Shawn Hill | 220.0 | 1996 | |
| 94 | Bob Harris | 220.0 | 1995 | |
| 94 | Jim Unknown | 220.0 | 1983 |
