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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Robert Carson RP | 2 | 6 | 13 | 3.36 | 56 | 0 | 59.0 | 52 | 23 | 22 | 8 | 20 | 53 | 1.22 | .232 | .268 | 0.6 |
| Kyle Hendricks SP | 13 | 8 | 0 | 4.17 | 33 | 33 | 220.0 | 209 | 108 | 102 | 25 | 58 | 178 | 1.21 | .248 | .285 | 5.0 |
| David Sanders RP | 2 | 1 | 1 | 4.58 | 44 | 0 | 39.1 | 37 | 20 | 20 | 3 | 23 | 47 | 1.53 | .239 | .321 | 0.8 |
| George Frazier RP | 3 | 1 | 0 | 4.65 | 56 | 0 | 69.2 | 74 | 42 | 36 | 10 | 28 | 53 | 1.46 | .272 | .302 | 0.3 |
| Mal Moss RP | 0 | 1 | 0 | 4.67 | 39 | 0 | 54.0 | 55 | 30 | 28 | 8 | 22 | 39 | 1.43 | .261 | .287 | 0.0 |
| Luis Castillo SP | 7 | 15 | 0 | 5.14 | 30 | 30 | 187.1 | 179 | 115 | 107 | 41 | 84 | 135 | 1.40 | .252 | .255 | -0.1 |
| John Miller SP | 2 | 3 | 0 | 5.56 | 39 | 8 | 103.2 | 109 | 68 | 64 | 12 | 67 | 79 | 1.70 | .276 | .310 | 0.3 |
| Cliff Lee SP | 8 | 11 | 0 | 5.76 | 31 | 31 | 170.1 | 198 | 122 | 109 | 23 | 84 | 134 | 1.66 | .292 | .330 | 1.7 |
| Bob Kline RP | 5 | 5 | 2 | 6.42 | 56 | 0 | 61.2 | 76 | 49 | 44 | 12 | 38 | 67 | 1.85 | .304 | .366 | -0.1 |
| David Carpenter CL | 4 | 11 | 13 | 7.10 | 58 | 0 | 52.0 | 72 | 41 | 41 | 12 | 20 | 53 | 1.77 | .327 | .385 | -0.5 |
| Jake Peavy SP | 6 | 17 | 0 | 7.30 | 29 | 29 | 160.1 | 193 | 138 | 130 | 33 | 89 | 142 | 1.76 | .298 | .333 | 0.2 |
| Jose Lima SP | 5 | 22 | 0 | 7.39 | 31 | 31 | 180.1 | 229 | 158 | 148 | 45 | 67 | 140 | 1.64 | .307 | .325 | -0.3 |
| Jeff Reardon RP | 2 | 1 | 2 | 7.40 | 54 | 0 | 62.0 | 86 | 57 | 51 | 14 | 40 | 68 | 2.03 | .327 | .389 | -0.6 |
| Joe Jimenez RP | 0 | 1 | 0 | 8.00 | 8 | 0 | 9.0 | 13 | 10 | 8 | 3 | 7 | 7 | 2.22 | .342 | .345 | -0.4 |
