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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Bob O'Brien | 1999-1999 | .000 | 0 | 0 | 2 | 1 | 1 | 4.26 | 10 |
| Charlie O'Brien | 2000-2000 | .214 | 2 | 10 | 0 | 0 | 0 | 0.00 | 0 |
| Paul O'Dea | 1991-1991 | .226 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Billy O'Dell | 1980-1980 | .000 | 0 | 0 | 5 | 6 | 0 | 4.95 | 26 |
| Troy O'Leary | 1980-1987 | .203 | 3 | 42 | 0 | 0 | 0 | 0.00 | 0 |
| Ryan O'Rourke | 1982-1985 | .000 | 0 | 0 | 9 | 6 | 10 | 3.28 | 100 |
| Denny O'Toole | 1980-1987 | .000 | 0 | 0 | 23 | 12 | 16 | 3.32 | 204 |
| Jake Odorizzi | 1990-1998 | .000 | 0 | 0 | 50 | 63 | 3 | 5.49 | 614 |
| Jose Offerman | 2000-2000 | .240 | 7 | 32 | 0 | 0 | 0 | 0.00 | 0 |
| Bruce Ogrodowski | 1980-1981 | .222 | 1 | 15 | 0 | 0 | 0 | 0.00 | 0 |
| John Olerud | 1980-1984 | .294 | 65 | 270 | 0 | 0 | 0 | 0.00 | 0 |
| Tony Oliva | 1982-1995 | .279 | 125 | 745 | 0 | 0 | 0 | 0.00 | 0 |
| Edward Olivares | 1982-1985 | .221 | 3 | 20 | 0 | 0 | 0 | 0.00 | 0 |
| Omar Olivares | 1980-1993 | .190 | 1 | 1 | 135 | 138 | 0 | 4.13 | 1603 |
| Joe Oliver | 1991-2000 | .250 | 15 | 72 | 0 | 0 | 0 | 0.00 | 0 |
| Lester Oliveros | 1980-1984 | .000 | 0 | 0 | 13 | 8 | 4 | 4.63 | 117 |
| Ole Olsen | 1988-1994 | .000 | 0 | 0 | 15 | 9 | 2 | 3.90 | 212 |
| Scott Olsen | 1980-1983 | .000 | 0 | 0 | 15 | 21 | 0 | 4.90 | 228 |
| Vern Olsen | 1994-2000 | .000 | 0 | 0 | 85 | 61 | 0 | 4.28 | 1012 |
| Garrett Olson | 1989-2000 | .000 | 0 | 0 | 45 | 63 | 305 | 2.63 | 466 |
| Tyler Olson | 1980-1985 | .000 | 0 | 0 | 4 | 3 | 1 | 3.84 | 45 |
| Steve Ontiveros | 1984-1999 | .266 | 97 | 807 | 0 | 0 | 0 | 0.00 | 0 |
| Tony Ordenana | 1995-2000 | .209 | 19 | 79 | 0 | 0 | 0 | 0.00 | 0 |
| Kevin Orie | 1980-1985 | .216 | 44 | 327 | 0 | 0 | 0 | 0.00 | 0 |
| Joe Orsulak | 1996-2000 | .296 | 77 | 407 | 0 | 0 | 0 | 0.00 | 0 |
| Phil Ortega | 1996-2000 | .000 | 0 | 0 | 57 | 46 | 0 | 4.10 | 752 |
| Jose Ortiz | 1990-1993 | .245 | 2 | 18 | 0 | 0 | 0 | 0.00 | 0 |
| Jose Ortiz | 1980-1985 | .241 | 5 | 88 | 0 | 0 | 0 | 0.00 | 0 |
| Bob Osborn | 1998-1999 | .000 | 0 | 0 | 2 | 4 | 0 | 6.37 | 32 |
| Tiny Osborne | 1980-1987 | .000 | 0 | 0 | 53 | 82 | 0 | 4.21 | 813 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Bill Oster | 1986-1986 | .000 | 0 | 0 | 0 | 0 | 0 | 10.50 | 1 |
| Antonio Osuna | 1988-1994 | .000 | 0 | 0 | 9 | 2 | 5 | 3.84 | 89 |
| Roy Oswalt | 1988-2000 | .000 | 0 | 0 | 202 | 103 | 0 | 3.48 | 1950 |
| Akinori Otsuka | 1981-1989 | .000 | 0 | 0 | 38 | 34 | 74 | 3.59 | 413 |
| Mel Ott | 1984-1995 | .266 | 193 | 713 | 0 | 0 | 0 | 0.00 | 0 |
| Dave Otto | 1998-2000 | .000 | 0 | 0 | 8 | 5 | 14 | 4.79 | 77 |
| Johnny Oulliber | 1992-1996 | .247 | 2 | 25 | 0 | 0 | 0 | 0.00 | 0 |
| William Outen | 1983-1990 | .213 | 98 | 346 | 0 | 0 | 0 | 0.00 | 0 |
| Lyle Overbay | 1983-1983 | .143 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Stubby Overmire | 1980-1982 | .000 | 0 | 0 | 28 | 29 | 0 | 4.30 | 146 |
| Johan Oviedo | 1993-2000 | .000 | 0 | 0 | 17 | 22 | 1 | 6.19 | 250 |
| Larry Owen | 1994-1996 | .083 | 1 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Eric Owens | 1990-1994 | .244 | 7 | 60 | 0 | 0 | 0 | 0.00 | 0 |
| Jayhawk Owens | 1980-1985 | .249 | 10 | 35 | 0 | 0 | 0 | 0.00 | 0 |
| Chris Owings | 1990-1996 | .254 | 46 | 237 | 0 | 0 | 0 | 0.00 | 0 |
| Marcell Ozuna | 1990-2000 | .283 | 298 | 1050 | 0 | 0 | 0 | 0.00 | 0 |
