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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Freddie Toliver | 11.27 | 1980-1988 | |
| 2 | Bill Scherrer# | 10.95 | 1993-2000 | |
| 3 | Daisuke Matsuzaka | 10.14 | 1986-1997 | |
| 4 | Devin Williams | 9.84 | 1980-1994 | |
| 5 | Tommy Boggs# | 9.80 | 1997-2000 | |
| 6 | Foster Edwards# | 9.66 | 1983-2000 | |
| 7 | Bob Kelly# | 9.64 | 1988-2000 | |
| 8 | Dizzy Dean# | 9.58 | 1993-2000 | |
| 9 | Don Drysdale# | 9.25 | 1999-2000 | |
| 10 | Jose Rijo# | 8.94 | 1993-2000 | |
| 11 | Blake Snell# | 8.92 | 1988-2000 | |
| 12 | Scott Sanderson | 8.83 | 1986-1994 | |
| 13 | Joe Krakauskas | 8.50 | 1984-1991 | |
| 14 | Shawn Chacon# | 8.45 | 1987-2000 | |
| 15 | Tim Wakefield# | 8.22 | 1991-1997 | |
| 16 | Red Munger# | 8.21 | 1993-2000 | |
| 17 | Mark Langston* | 8.18 | 1980-1994 | |
| 18 | Paul Erickson# | 8.15 | 1998-2000 | |
| 19 | Tommy Milone# | 8.13 | 1999-2000 | |
| 20 | Rick Rhoden# | 8.02 | 1994-2000 | |
| 21 | Daniel Wright | 8.00 | 1989-1996 | |
| 22 | Jack Sanford# | 7.92 | 1994-2000 | |
| 22 | Carl Hubbell# | 7.92 | 1992-2000 | |
| 24 | Tom Gordon# | 7.90 | 1993-2000 | |
| 25 | Sam McDowell | 7.85 | 1986-1999 | |
| 26 | Jhoan Duran# | 7.81 | 1988-2000 | |
| 27 | Brian Kingman | 7.79 | 1989-1998 | |
| 28 | Tony Saunders# | 7.77 | 1988-1993 | |
| 29 | Steven Matz# | 7.75 | 1989-2000 | |
| 30 | Dustin Hermanson# | 7.63 | 1987-2000 | |
| 31 | Dave Borkowski | 7.61 | 1984-1999 | |
| 31 | Ian Snell | 7.61 | 1980-1992 | |
| 33 | John Patterson | 7.57 | 1981-1997 | |
| 34 | Esteban Loaiza# | 7.56 | 1988-2000 | |
| 34 | Luke Weaver# | 7.56 | 1992-2000 | |
| 36 | Vern Olsen# | 7.51 | 1994-2000 | |
| 37 | Sonny Gray# | 7.49 | 1997-2000 | |
| 37 | Joel Zumaya# | 7.49 | 1992-2000 | |
| 39 | Hal Newhouser | 7.47 | 1985-1998 | |
| 40 | Gordon Jones | 7.44 | 1986-1995 | |
| 41 | Kevin Ritz# | 7.41 | 1997-2000 | |
| 41 | Sterling Hitchcock | 7.41 | 1980-1990 | |
| 43 | Robbie Ray | 7.33 | 1980-1992 | |
| 44 | Kyle Freeland# | 7.32 | 1988-2000 | |
| 45 | Henderson Alvarez III# | 7.24 | 1996-2000 | |
| 46 | Hector Fajardo | 7.20 | 1987-1995 | |
| 47 | Mike Nagy# | 7.16 | 1992-2000 | |
| 47 | Chad Gaudin | 7.16 | 1981-1993 | |
| 49 | Len Barker | 7.12 | 1980-1992 | |
| 49 | Omar Daal | 7.12 | 1980-1990 | |
| 51 | Blake Stein | 7.11 | 1980-1988 | |
| 52 | Bobby Shantz | 7.07 | 1981-1997 | |
| 52 | Milt Pappas | 7.07 | 1984-1993 | |
| 54 | Red Witt# | 7.04 | 1982-2000 | |
| 55 | Kenta Maeda | 7.03 | 1982-1994 | |
| 56 | Chris Capuano | 7.02 | 1994-1998 | |
| 57 | Sonny Siebert | 6.98 | 1982-1999 | |
| 58 | Bruce Howard# | 6.97 | 1990-2000 | |
| 58 | Tyler Anderson | 6.97 | 1980-1988 | |
| 58 | Jeff Sellers | 6.97 | 1980-1998 | |
| 61 | John Axford# | 6.95 | 1986-2000 | |
| 61 | Art Ceccarelli | 6.95 | 1980-1989 | |
| 63 | Dave Veres# | 6.92 | 1991-2000 | |
| 64 | Jim Colborn# | 6.90 | 1996-2000 | |
| 64 | John Fulgham# | 6.90 | 1990-2000 | |
| 66 | Bob Anderson | 6.86 | 1980-1997 | |
| 66 | Bob Friend | 6.86 | 1980-1998 | |
| 68 | Chris Hatcher# | 6.79 | 1990-2000 | |
| 69 | Jakob Junis | 6.75 | 1984-1997 | |
| 70 | Urbano Lugo | 6.70 | 1980-1993 | |
| 71 | Paul Moskau | 6.69 | 1982-1987 | |
| 71 | Earl Francis# | 6.69 | 1991-2000 | |
| 73 | Joey Hamilton# | 6.67 | 1998-2000 | |
| 74 | Homer Bailey# | 6.66 | 1991-2000 | |
| 75 | Bill Lee# | 6.65 | 1991-2000 | |
| 76 | Wade Miley# | 6.64 | 1988-1995 | |
| 77 | Roy Oswalt# | 6.63 | 1988-2000 | |
| 78 | Walker Buehler# | 6.61 | 1988-2000 | |
| 78 | Brayan Bello# | 6.61 | 1987-2000 | |
| 80 | Doug Rau# | 6.57 | 1992-2000 | |
| 81 | Hub Pruett | 6.56 | 1980-1994 | |
| 82 | Les Tietje | 6.55 | 1984-1992 | |
| 82 | Albie Lopez | 6.55 | 1984-2000 | |
| 84 | Joe Coleman | 6.54 | 1981-1994 | |
| 85 | Kip Wells# | 6.53 | 1986-2000 | |
| 86 | Jim York# | 6.50 | 1982-2000 | |
| 87 | Hiroki Kuroda# | 6.43 | 1993-2000 | |
| 87 | Mike Ryba# | 6.43 | 1997-2000 | |
| 89 | John Candelaria# | 6.34 | 1980-2000 | |
| 90 | Atley Donald | 6.27 | 1989-1997 | |
| 90 | Jeff Samardzija# | 6.27 | 1985-1997 | |
| 92 | Jonathan Loaisiga | 6.26 | 1983-1993 | |
| 93 | Dave Dravecky | 6.25 | 1987-1997 | |
| 93 | Mark Buehrle# | 6.25 | 1980-2000 | |
| 95 | John Miller# | 6.24 | 1986-2000 | |
| 96 | John Montefusco | 6.22 | 1986-1997 | |
| 97 | Ed Hanyzewski# | 6.19 | 1994-2000 | |
| 98 | Mike LaCoss | 6.09 | 1987-1995 | |
| 99 | Matt Guerrier | 6.05 | 1985-1999 | |
| 100 | Omar Olivares | 6.03 | 1980-1993 |
