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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Bobby Shantz | 32 | 1981-1997 | |
| 2 | Chad Gaudin | 25 | 1981-1993 | |
| 3 | Joe Coleman | 23 | 1981-1994 | |
| 4 | Barry Zito | 21 | 1980-1994 | |
| 5 | Barry Moore | 18 | 1980-1992 | |
| 6 | Mark Langston* | 17 | 1980-1994 | |
| 6 | Steven Matz# | 17 | 1989-2000 | |
| 6 | Jeff Sellers | 17 | 1980-1998 | |
| 9 | Daisuke Matsuzaka | 16 | 1986-1997 | |
| 10 | La Marr Hoyt# | 15 | 1985-2000 | |
| 10 | Carl Hubbell# | 15 | 1992-2000 | |
| 10 | Robbie Ray | 15 | 1980-1992 | |
| 13 | John Candelaria# | 14 | 1980-2000 | |
| 13 | Omar Olivares | 14 | 1980-1993 | |
| 13 | Rick Rhoden# | 14 | 1994-2000 | |
| 13 | Jim Willis | 14 | 1980-1990 | |
| 17 | Chris Bosio | 13 | 1980-1998 | |
| 17 | Don Drysdale# | 13 | 1999-2000 | |
| 17 | Roy Oswalt# | 13 | 1988-2000 | |
| 17 | Scott Sanderson | 13 | 1986-1994 | |
| 17 | Red Witt# | 13 | 1982-2000 | |
| 22 | Mark Buehrle# | 12 | 1980-2000 | |
| 22 | Shawn Chacon# | 12 | 1987-2000 | |
| 22 | Sterling Hitchcock | 12 | 1980-1990 | |
| 22 | Urbano Lugo | 12 | 1980-1993 | |
| 22 | Wayne Schurr# | 12 | 1986-1999 | |
| 27 | Jhoan Duran# | 11 | 1988-2000 | |
| 27 | Red Embree | 11 | 1981-1994 | |
| 27 | Tom Gordon# | 11 | 1993-2000 | |
| 27 | Esteban Loaiza# | 11 | 1988-2000 | |
| 27 | John Patterson | 11 | 1981-1997 | |
| 27 | Gaylord Perry | 11 | 1980-1995 | |
| 27 | Doug Rau# | 11 | 1992-2000 | |
| 27 | Sonny Siebert | 11 | 1982-1999 | |
| 27 | Blake Snell# | 11 | 1988-2000 | |
| 36 | Ray Bare# | 10 | 1987-2000 | |
| 36 | Tom Brewer# | 10 | 1997-2000 | |
| 36 | Jim Colborn# | 10 | 1996-2000 | |
| 36 | Jakob Junis | 10 | 1984-1997 | |
| 36 | Paul Moskau | 10 | 1982-1987 | |
| 36 | Ian Snell | 10 | 1980-1992 | |
| 42 | Henderson Alvarez III# | 9 | 1996-2000 | |
| 42 | John Axford# | 9 | 1986-2000 | |
| 42 | Art Ceccarelli | 9 | 1980-1989 | |
| 42 | Jim Donohue | 9 | 1981-1994 | |
| 42 | Dave Goltz# | 9 | 1990-1998 | |
| 42 | Ed Hanyzewski# | 9 | 1994-2000 | |
| 42 | Dallas Keuchel | 9 | 1980-1986 | |
| 42 | Red Munger# | 9 | 1993-2000 | |
| 42 | Jose Rijo# | 9 | 1993-2000 | |
| 51 | Kyle Freeland# | 8 | 1988-2000 | |
| 51 | Jim Golden# | 8 | 1990-2000 | |
| 51 | Chris Holt# | 8 | 1993-2000 | |
| 51 | Hiroki Kuroda# | 8 | 1993-2000 | |
| 51 | Albie Lopez | 8 | 1984-2000 | |
| 51 | Kenta Maeda | 8 | 1982-1994 | |
| 51 | Tommy Milone# | 8 | 1999-2000 | |
| 51 | Vern Olsen# | 8 | 1994-2000 | |
| 51 | Tim Wakefield# | 8 | 1991-1997 | |
| 60 | Clayton Andrews | 7 | 1980-1997 | |
| 60 | Omar Daal | 7 | 1980-1990 | |
| 60 | Dizzy Dean# | 7 | 1993-2000 | |
| 60 | Jack Fisher# | 7 | 1994-2000 | |
| 60 | Sonny Gray# | 7 | 1997-2000 | |
| 60 | Mickey Harris# | 7 | 1986-1999 | |
| 60 | Ray Herbert# | 7 | 1992-2000 | |
| 60 | Dustin Hermanson# | 7 | 1987-2000 | |
| 60 | Gordon Jones | 7 | 1986-1995 | |
| 60 | Jon Matlack | 7 | 1981-1999 | |
| 60 | John Montefusco | 7 | 1986-1997 | |
| 60 | Phil Niekro | 7 | 1983-1998 | |
| 60 | Jose Quintana | 7 | 1980-1984 | |
| 60 | Jeff Samardzija# | 7 | 1985-1997 | |
| 60 | Warren Spahn | 7 | 1980-1995 | |
| 60 | Jim York# | 7 | 1982-2000 | |
| 76 | Mike Adams | 6 | 1980-1988 | |
| 76 | Bob Anderson | 6 | 1980-1997 | |
| 76 | Walker Buehler# | 6 | 1988-2000 | |
| 76 | Jin-ho Cho | 6 | 1980-1991 | |
| 76 | Kevin Gregg# | 6 | 1989-2000 | |
| 76 | Chris Hatcher# | 6 | 1990-2000 | |
| 76 | Bob Kelly# | 6 | 1988-2000 | |
| 76 | John King | 6 | 1980-1991 | |
| 76 | Sean Manaea# | 6 | 1987-2000 | |
| 76 | Kevin McCarthy | 6 | 1985-1998 | |
| 76 | Bob Moose | 6 | 1980-1989 | |
| 76 | Milt Pappas | 6 | 1984-1993 | |
| 76 | Jay Powell# | 6 | 1989-2000 | |
| 76 | Mike Ryba# | 6 | 1997-2000 | |
| 76 | Tony Saunders# | 6 | 1988-1993 | |
| 76 | Zeke Spruill | 6 | 1980-1992 | |
| 76 | Sammy Stewart | 6 | 1980-1986 | |
| 76 | Joel Zumaya# | 6 | 1992-2000 | |
| 94 | Raul Alcantara# | 5 | 1982-2000 | |
| 94 | Tyler Anderson | 5 | 1980-1988 | |
| 94 | Sean Bergman | 5 | 1980-1990 | |
| 94 | Atley Donald | 5 | 1989-1997 | |
| 94 | Bob Friend | 5 | 1980-1998 | |
| 94 | Dillon Gee# | 5 | 1993-2000 | |
| 94 | Jason Grilli | 5 | 1980-1986 |
