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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Devin Williams | 8.57 | 1980-1994 | |
| 2 | Dave Boswell# | 8.42 | 1995-2000 | |
| 3 | Jose Rijo# | 8.14 | 1993-2000 | |
| 4 | Tom Gordon# | 8.12 | 1993-2000 | |
| 5 | Blake Snell# | 8.05 | 1988-2000 | |
| 6 | Sam McDowell | 7.87 | 1986-1999 | |
| 7 | Jake Peavy# | 7.77 | 1995-2000 | |
| 8 | Rex Brothers# | 7.62 | 1986-2000 | |
| 9 | Phil Ortega# | 7.50 | 1996-2000 | |
| 10 | Jack Sanford# | 7.34 | 1994-2000 | |
| 11 | Kevin Siegrist | 7.32 | 1980-1995 | |
| 12 | Daisuke Matsuzaka | 7.30 | 1986-1997 | |
| 13 | Jack Fisher# | 7.26 | 1994-2000 | |
| 14 | Dave Veres# | 7.24 | 1991-2000 | |
| 14 | Hal Newhouser | 7.24 | 1985-1998 | |
| 16 | Bobby Shantz | 7.23 | 1981-1997 | |
| 17 | Todd Stottlemyre | 7.19 | 1983-1995 | |
| 17 | Dizzy Dean# | 7.19 | 1993-2000 | |
| 17 | Vern Olsen# | 7.19 | 1994-2000 | |
| 20 | Robbie Ray | 7.18 | 1980-1992 | |
| 21 | Jhoan Duran# | 7.13 | 1988-2000 | |
| 22 | Jose Lima# | 7.12 | 1995-2000 | |
| 23 | Scott Sanderson | 7.11 | 1986-1994 | |
| 24 | Carl Hubbell# | 7.10 | 1992-2000 | |
| 25 | Mark Langston* | 7.08 | 1980-1994 | |
| 26 | Kyle Hendricks# | 7.06 | 1996-2000 | |
| 26 | Gordon Jones | 7.06 | 1986-1995 | |
| 26 | Luke Weaver# | 7.06 | 1992-2000 | |
| 29 | Ian Snell | 7.05 | 1980-1992 | |
| 30 | Johnny Klippstein# | 6.99 | 1993-1999 | |
| 31 | Dean Chance# | 6.90 | 1993-2000 | |
| 31 | John Patterson | 6.90 | 1981-1997 | |
| 33 | Reyes Moronta | 6.86 | 1980-1991 | |
| 34 | Steven Matz# | 6.84 | 1989-2000 | |
| 35 | Mickey Lolich# | 6.82 | 1988-1997 | |
| 36 | Red Munger# | 6.81 | 1993-2000 | |
| 36 | Dave Borkowski | 6.81 | 1984-1999 | |
| 38 | Rick Rhoden# | 6.73 | 1994-2000 | |
| 39 | Aaron Nola | 6.71 | 1989-1997 | |
| 40 | Les Tietje | 6.70 | 1984-1992 | |
| 41 | Jeff Sellers | 6.67 | 1980-1998 | |
| 42 | Terry Felton | 6.65 | 1985-1997 | |
| 42 | Matt Young# | 6.65 | 1995-2000 | |
| 42 | Ike Delock | 6.65 | 1985-1996 | |
| 45 | Bill Burbach | 6.63 | 1983-1998 | |
| 46 | Jason Hammel# | 6.60 | 1989-2000 | |
| 46 | Al Javery | 6.60 | 1984-1988 | |
| 48 | Sterling Hitchcock | 6.58 | 1980-1990 | |
| 48 | Kip Wells# | 6.58 | 1986-2000 | |
| 50 | Mickey Harris# | 6.57 | 1986-1999 | |
| 51 | Earl Francis# | 6.54 | 1991-2000 | |
| 51 | Gary Bell# | 6.54 | 1990-2000 | |
| 53 | Homer Bailey# | 6.53 | 1991-2000 | |
| 54 | Art Ceccarelli | 6.50 | 1980-1989 | |
| 54 | Bill Gullickson# | 6.50 | 1991-1999 | |
| 56 | Jim Golden# | 6.49 | 1990-2000 | |
| 57 | Kenta Maeda | 6.46 | 1982-1994 | |
| 57 | Kevin Tapani# | 6.46 | 1995-2000 | |
| 57 | Zach Davies# | 6.46 | 1995-2000 | |
| 60 | Ben Sheets# | 6.44 | 1983-1999 | |
| 60 | Ed Hanyzewski# | 6.44 | 1994-2000 | |
| 60 | Tim Wakefield# | 6.44 | 1991-1997 | |
| 60 | John Axford# | 6.44 | 1986-2000 | |
| 64 | Dustin Hermanson# | 6.43 | 1987-2000 | |
| 65 | John Montefusco | 6.41 | 1986-1997 | |
| 66 | Chad Gaudin | 6.39 | 1981-1993 | |
| 67 | Jeff Samardzija# | 6.38 | 1985-1997 | |
| 68 | Tim Belcher# | 6.35 | 1987-2000 | |
| 69 | Bill Butler | 6.34 | 1983-1999 | |
| 70 | Teddy Higuera# | 6.33 | 1992-2000 | |
| 70 | Sonny Siebert | 6.33 | 1982-1999 | |
| 72 | Raul Alcantara# | 6.29 | 1982-2000 | |
| 72 | Roy Oswalt# | 6.29 | 1988-2000 | |
| 72 | Chris Hatcher# | 6.29 | 1990-2000 | |
| 75 | Paul Moskau | 6.28 | 1982-1987 | |
| 76 | Jimmy Key# | 6.26 | 1988-1997 | |
| 77 | Kyle Freeland# | 6.25 | 1988-2000 | |
| 78 | John Candelaria# | 6.24 | 1980-2000 | |
| 78 | Doug Rau# | 6.24 | 1992-2000 | |
| 80 | Carl Fischer | 6.20 | 1980-1990 | |
| 80 | Jose Santiago | 6.20 | 1985-1996 | |
| 82 | Tony Saunders# | 6.19 | 1988-1993 | |
| 82 | Jakob Junis | 6.19 | 1984-1997 | |
| 82 | Red Witt# | 6.19 | 1982-2000 | |
| 85 | Dillon Gee# | 6.18 | 1993-2000 | |
| 86 | Hub Pruett | 6.17 | 1980-1994 | |
| 87 | Urbano Lugo | 6.16 | 1980-1993 | |
| 88 | Red Embree | 6.15 | 1981-1994 | |
| 88 | Barry Zito | 6.15 | 1980-1994 | |
| 88 | Dick Drott | 6.15 | 1980-1994 | |
| 91 | Bob Moose | 6.13 | 1980-1989 | |
| 91 | Esteban Loaiza# | 6.13 | 1988-2000 | |
| 91 | Bob Anderson | 6.13 | 1980-1997 | |
| 94 | Sean Manaea# | 6.11 | 1987-2000 | |
| 95 | Buddy Carlyle | 6.08 | 1980-1992 | |
| 95 | La Marr Hoyt# | 6.08 | 1985-2000 | |
| 97 | Jon Matlack | 6.07 | 1981-1999 | |
| 98 | Shawn Chacon# | 6.06 | 1987-2000 | |
| 99 | Les Cain | 6.05 | 1980-1995 | |
| 99 | Pat Combs# | 6.05 | 1992-2000 |
