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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | John Candelaria# | 3293 | 1980-2000 | |
| 2 | Mark Buehrle# | 3078 | 1980-2000 | |
| 3 | Mark Langston* | 2716 | 1980-1994 | |
| 4 | Jeff Sellers | 2685 | 1980-1998 | |
| 5 | John Patterson | 2608 | 1981-1997 | |
| 6 | Jon Matlack | 2590 | 1981-1999 | |
| 7 | Bob Anderson | 2397 | 1980-1997 | |
| 8 | Blake Snell# | 2388 | 1988-2000 | |
| 9 | Bob Friend | 2359 | 1980-1998 | |
| 10 | Bobby Shantz | 2271 | 1981-1997 | |
| 11 | Robbie Ray | 2211 | 1980-1992 | |
| 12 | Hal Newhouser | 2160 | 1985-1998 | |
| 13 | Barry Zito | 2150 | 1980-1994 | |
| 14 | Esteban Loaiza# | 2071 | 1988-2000 | |
| 15 | Ian Snell | 2054 | 1980-1992 | |
| 16 | Sonny Siebert | 2028 | 1982-1999 | |
| 17 | Warren Spahn | 1990 | 1980-1995 | |
| 18 | Sam McDowell | 1982 | 1986-1999 | |
| 19 | Roy Oswalt# | 1950 | 1988-2000 | |
| 20 | Don Kaiser# | 1888 | 1984-2000 | |
| 21 | Red Witt# | 1874 | 1982-2000 | |
| 22 | Ben Sheets# | 1863 | 1983-1999 | |
| 23 | Kenta Maeda | 1856 | 1982-1994 | |
| 24 | Walker Buehler# | 1808 | 1988-2000 | |
| 25 | Kyle Freeland# | 1793 | 1988-2000 | |
| 26 | Todd Stottlemyre | 1786 | 1983-1995 | |
| 27 | Chris Bosio | 1780 | 1980-1998 | |
| 28 | Tim Belcher# | 1742 | 1987-2000 | |
| 29 | Mickey Harris# | 1734 | 1986-1999 | |
| 30 | Bill Bevens | 1714 | 1982-1993 | |
| 31 | Jerad Eickhoff | 1713 | 1981-1997 | |
| 32 | Jason Hammel# | 1690 | 1989-2000 | |
| 33 | Bill Lee | 1680 | 1983-1999 | |
| 34 | Sean Manaea# | 1663 | 1987-2000 | |
| 35 | Gaylord Perry | 1653 | 1980-1995 | |
| 36 | Kip Wells# | 1650 | 1986-2000 | |
| 37 | Daisuke Matsuzaka | 1627 | 1986-1997 | |
| 38 | Mickey Lolich# | 1620 | 1988-1997 | |
| 39 | Red Embree | 1611 | 1981-1994 | |
| 40 | Omar Olivares | 1603 | 1980-1993 | |
| 41 | Carl Hubbell# | 1578 | 1992-2000 | |
| 42 | Craig Swan | 1574 | 1980-1993 | |
| 43 | Dustin Hermanson# | 1568 | 1987-2000 | |
| 44 | John Montefusco | 1567 | 1986-1997 | |
| 45 | Jim Merritt | 1556 | 1980-1994 | |
| 46 | Don Sutton# | 1552 | 1987-1998 | |
| 47 | La Marr Hoyt# | 1547 | 1985-2000 | |
| 48 | Sterling Hitchcock | 1543 | 1980-1990 | |
| 49 | Tom Gordon# | 1537 | 1993-2000 | |
| 50 | Steven Matz# | 1525 | 1989-2000 | |
| 51 | John Miller# | 1506 | 1986-2000 | |
| 52 | Foster Edwards# | 1504 | 1983-2000 | |
| 53 | Urbano Lugo | 1497 | 1980-1993 | |
| 54 | Phil Niekro | 1494 | 1983-1998 | |
| 55 | Jakob Junis | 1493 | 1984-1997 | |
| 56 | Len Barker | 1480 | 1980-1992 | |
| 57 | Joe Coleman | 1456 | 1981-1994 | |
| 58 | Jimmy Key# | 1444 | 1988-1997 | |
| 59 | Chad Gaudin | 1432 | 1981-1993 | |
| 60 | Aaron Nola | 1416 | 1989-1997 | |
| 61 | Dizzy Dean# | 1414 | 1993-2000 | |
| 62 | Jose Rijo# | 1406 | 1993-2000 | |
| 63 | Luke Weaver# | 1375 | 1992-2000 | |
| 64 | Carl Fischer | 1369 | 1980-1990 | |
| 65 | Bob Moose | 1346 | 1980-1989 | |
| 66 | Jon Garland# | 1330 | 1987-2000 | |
| 67 | Dean Chance# | 1318 | 1993-2000 | |
| 68 | Gary Bell# | 1312 | 1990-2000 | |
| 69 | Hub Pruett | 1294 | 1980-1994 | |
| 70 | Scott Sanderson | 1292 | 1986-1994 | |
| 71 | Art Ceccarelli | 1281 | 1980-1989 | |
| 72 | Odalis Perez | 1276 | 1985-1995 | |
| 73 | Barry Moore | 1275 | 1980-1992 | |
| 74 | Albie Lopez | 1264 | 1984-2000 | |
| 75 | Red Munger# | 1262 | 1993-2000 | |
| 76 | Homer Bailey# | 1250 | 1991-2000 | |
| 76 | Blake Stein | 1250 | 1980-1988 | |
| 78 | Teddy Higuera# | 1241 | 1992-2000 | |
| 79 | Earl Francis# | 1228 | 1991-2000 | |
| 80 | Jack Fisher# | 1223 | 1994-2000 | |
| 80 | Luke Hochevar | 1223 | 1980-1996 | |
| 82 | Dave Boswell# | 1191 | 1995-2000 | |
| 83 | Jim Rooker | 1181 | 1980-1990 | |
| 84 | Chris Bassitt | 1170 | 1986-1996 | |
| 85 | Brayan Bello# | 1165 | 1987-2000 | |
| 86 | Jim Golden# | 1159 | 1990-2000 | |
| 87 | Ray Bare# | 1158 | 1987-2000 | |
| 88 | Bill Gullickson# | 1154 | 1991-1999 | |
| 89 | Ike Delock | 1146 | 1985-1996 | |
| 89 | Doug Rau# | 1146 | 1992-2000 | |
| 91 | Rollie Sheldon | 1134 | 1984-1995 | |
| 92 | Johnny Klippstein# | 1127 | 1993-1999 | |
| 93 | Phil Marchildon | 1120 | 1980-1988 | |
| 94 | Devin Williams | 1113 | 1980-1994 | |
| 95 | Mike Nagy# | 1103 | 1992-2000 | |
| 96 | Hiroki Kuroda# | 1094 | 1993-2000 | |
| 97 | Dillon Gee# | 1083 | 1993-2000 | |
| 98 | Lucas Giolito | 1077 | 1985-1995 | |
| 99 | Chris Holt# | 1070 | 1993-2000 | |
| 100 | Omar Daal | 1069 | 1980-1990 |
