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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SHO | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Carl Hubbell# | 27 | 1992-2000 | |
| 1 | Mark Langston* | 27 | 1980-1994 | |
| 3 | John Patterson | 26 | 1981-1997 | |
| 4 | Jon Matlack | 25 | 1981-1999 | |
| 5 | John Candelaria# | 24 | 1980-2000 | |
| 6 | Esteban Loaiza# | 23 | 1988-2000 | |
| 6 | Hal Newhouser | 23 | 1985-1998 | |
| 6 | Barry Zito | 23 | 1980-1994 | |
| 9 | Warren Spahn | 22 | 1980-1995 | |
| 10 | Mark Buehrle# | 18 | 1980-2000 | |
| 10 | Robbie Ray | 18 | 1980-1992 | |
| 10 | Jeff Sellers | 18 | 1980-1998 | |
| 13 | Bill Bevens | 17 | 1982-1993 | |
| 13 | Phil Niekro | 17 | 1983-1998 | |
| 13 | Roy Oswalt# | 17 | 1988-2000 | |
| 13 | Ian Snell | 17 | 1980-1992 | |
| 17 | Jason Hammel# | 16 | 1989-2000 | |
| 17 | Jakob Junis | 16 | 1984-1997 | |
| 17 | Mickey Lolich# | 16 | 1988-1997 | |
| 17 | Don Sutton# | 16 | 1987-1998 | |
| 17 | Craig Swan | 16 | 1980-1993 | |
| 17 | Les Tietje | 16 | 1984-1992 | |
| 23 | Bob Friend | 15 | 1980-1998 | |
| 23 | Sean Manaea# | 15 | 1987-2000 | |
| 25 | Jimmy Key# | 14 | 1988-1997 | |
| 25 | Sonny Siebert | 14 | 1982-1999 | |
| 27 | Ray Bare# | 13 | 1987-2000 | |
| 27 | Walker Buehler# | 13 | 1988-2000 | |
| 27 | Jerad Eickhoff | 13 | 1981-1997 | |
| 27 | John Montefusco | 13 | 1986-1997 | |
| 27 | Blake Snell# | 13 | 1988-2000 | |
| 32 | Bob Anderson | 12 | 1980-1997 | |
| 32 | Carl Fischer | 12 | 1980-1990 | |
| 32 | Kenta Maeda | 12 | 1982-1994 | |
| 32 | Phil Marchildon | 12 | 1980-1988 | |
| 36 | Mickey Harris# | 11 | 1986-1999 | |
| 36 | John Miller# | 11 | 1986-2000 | |
| 36 | Barry Moore | 11 | 1980-1992 | |
| 36 | Gaylord Perry | 11 | 1980-1995 | |
| 40 | Len Barker | 10 | 1980-1992 | |
| 40 | Chris Bassitt | 10 | 1986-1996 | |
| 40 | Tim Belcher# | 10 | 1987-2000 | |
| 40 | Sterling Hitchcock | 10 | 1980-1990 | |
| 40 | Jim Merritt | 10 | 1980-1994 | |
| 40 | Ben Sheets# | 10 | 1983-1999 | |
| 46 | Gary Bell# | 9 | 1990-2000 | |
| 46 | Dizzy Dean# | 9 | 1993-2000 | |
| 46 | Foster Edwards# | 9 | 1983-2000 | |
| 46 | Jack Fisher# | 9 | 1994-2000 | |
| 46 | Kyle Freeland# | 9 | 1988-2000 | |
| 46 | Red Munger# | 9 | 1993-2000 | |
| 46 | Odalis Perez | 9 | 1985-1995 | |
| 53 | Chris Bosio | 8 | 1980-1998 | |
| 53 | Ike Delock | 8 | 1985-1996 | |
| 53 | Bill Lee | 8 | 1983-1999 | |
| 53 | Sam McDowell | 8 | 1986-1999 | |
| 53 | Bob Moose | 8 | 1980-1989 | |
| 53 | Blake Stein | 8 | 1980-1988 | |
| 53 | Todd Stottlemyre | 8 | 1983-1995 | |
| 60 | Johnny Antonelli | 7 | 1980-1983 | |
| 60 | Chris Holt# | 7 | 1993-2000 | |
| 60 | Al Javery | 7 | 1984-1988 | |
| 60 | Hiroki Kuroda# | 7 | 1993-2000 | |
| 60 | Dutch Leonard | 7 | 1981-1992 | |
| 60 | Jose Lima# | 7 | 1995-2000 | |
| 60 | Steven Matz# | 7 | 1989-2000 | |
| 60 | Bobby Shantz | 7 | 1981-1997 | |
| 68 | Brayan Bello# | 6 | 1987-2000 | |
| 68 | Dave Boswell# | 6 | 1995-2000 | |
| 68 | Tom Buskey | 6 | 1980-1985 | |
| 68 | Art Ceccarelli | 6 | 1980-1989 | |
| 68 | Atley Donald | 6 | 1989-1997 | |
| 68 | Zach Duke | 6 | 1980-1983 | |
| 68 | Red Embree | 6 | 1981-1994 | |
| 68 | Bill Gullickson# | 6 | 1991-1999 | |
| 68 | Dallas Keuchel | 6 | 1980-1986 | |
| 68 | Ellis Kinder | 6 | 1984-1988 | |
| 68 | Albie Lopez | 6 | 1984-2000 | |
| 68 | Tiny Osborne | 6 | 1980-1987 | |
| 68 | Jose Quintana | 6 | 1980-1984 | |
| 68 | Doug Rau# | 6 | 1992-2000 | |
| 68 | Kevin Ritz# | 6 | 1997-2000 | |
| 68 | Jim Rooker | 6 | 1980-1990 | |
| 68 | Ismael Valdez | 6 | 1980-1990 | |
| 68 | Jim Willis | 6 | 1980-1990 | |
| 86 | Sean Bergman | 5 | 1980-1990 | |
| 86 | Tommy Boggs# | 5 | 1997-2000 | |
| 86 | Joe Coleman | 5 | 1981-1994 | |
| 86 | Pat Combs# | 5 | 1992-2000 | |
| 86 | Jose de Jesus | 5 | 1983-1986 | |
| 86 | Mike Flanagan# | 5 | 1991-1999 | |
| 86 | Earl Francis# | 5 | 1991-2000 | |
| 86 | Chad Gaudin | 5 | 1981-1993 | |
| 86 | Tom Gordon# | 5 | 1993-2000 | |
| 86 | Ted Gray | 5 | 1982-1997 | |
| 86 | Dustin Hermanson# | 5 | 1987-2000 | |
| 86 | Bruce Howard# | 5 | 1990-2000 | |
| 86 | Ken Johnson | 5 | 1980-1988 | |
| 86 | Pete Mikkelsen | 5 | 1980-1984 | |
| 86 | Vern Olsen# | 5 | 1994-2000 |
