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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jose Canseco# | 766 | 1981-2000 | |
| 2 | Hack Wilson# | 663 | 1983-2000 | |
| 3 | George Shuba# | 645 | 1983-2000 | |
| 4 | Don Young# | 520 | 1982-2000 | |
| 5 | Yogi Berra# | 501 | 1982-2000 | |
| 5 | Kirk Gibson | 501 | 1983-1999 | |
| 7 | Tommy Medica# | 495 | 1984-2000 | |
| 8 | Larry Walker | 481 | 1980-1995 | |
| 9 | Goose Goslin | 449 | 1980-1994 | |
| 10 | Rafael Palmeiro# | 440 | 1986-2000 | |
| 11 | José Abreu | 415 | 1987-2000 | |
| 12 | Eddie Mathews# | 369 | 1989-2000 | |
| 13 | Randal Grichuk | 359 | 1980-1995 | |
| 14 | Derrick May# | 351 | 1983-2000 | |
| 15 | Jason Bay | 349 | 1986-1998 | |
| 16 | Al Simmons# | 344 | 1990-2000 | |
| 17 | Bill Madlock | 329 | 1982-1997 | |
| 18 | Mike Schmidt# | 324 | 1990-2000 | |
| 19 | Cory Snyder# | 318 | 1988-2000 | |
| 20 | Evan Longoria | 314 | 1982-1995 | |
| 20 | Ken Singleton# | 314 | 1984-1999 | |
| 22 | Jay Buhner# | 310 | 1986-2000 | |
| 23 | Johnny Rizzo# | 309 | 1993-2000 | |
| 24 | Kevin McReynolds | 298 | 1980-1993 | |
| 24 | Marcell Ozuna# | 298 | 1990-2000 | |
| 26 | Teoscar Hernandez | 296 | 1983-1995 | |
| 27 | Ray Boone | 293 | 1982-1995 | |
| 27 | Ketel Marte# | 293 | 1988-2000 | |
| 29 | Derek Bell# | 288 | 1986-2000 | |
| 30 | Pedro Guerrero | 284 | 1983-1999 | |
| 30 | Calvin Pickering | 284 | 1980-1992 | |
| 32 | Phil Nevin | 282 | 1984-1997 | |
| 32 | Miguel Sanó# | 282 | 1991-2000 | |
| 34 | Dave Henderson | 277 | 1985-1999 | |
| 35 | Jorge Soler | 269 | 1982-1994 | |
| 36 | Dick Siebert | 268 | 1984-1999 | |
| 37 | Dansby Swanson | 265 | 1980-1995 | |
| 38 | Sixto Lezcano# | 264 | 1990-2000 | |
| 39 | Alex Bregman | 263 | 1980-1994 | |
| 40 | George Thomas | 259 | 1980-1999 | |
| 41 | Kyle Lewis | 258 | 1987-1999 | |
| 42 | George Canale | 257 | 1980-1990 | |
| 43 | Jim Bottomley# | 255 | 1991-2000 | |
| 43 | Dave Harris | 255 | 1980-1988 | |
| 45 | Johnny Grubb# | 250 | 1992-2000 | |
| 46 | Greg Luzinski# | 249 | 1991-2000 | |
| 46 | Andrew McCutchen | 249 | 1980-1993 | |
| 48 | Will Clark | 245 | 1984-1997 | |
| 48 | Kyle Tucker | 245 | 1980-1992 | |
| 50 | John Hale# | 239 | 1992-2000 | |
| 51 | Gene Green | 235 | 1986-1999 | |
| 52 | Eugenio Suárez# | 230 | 1991-2000 | |
| 53 | Joe Hauser# | 229 | 1996-2000 | |
| 54 | Gene Woodling | 225 | 1980-1994 | |
| 55 | Austin Hays | 224 | 1982-1997 | |
| 55 | Mike Lowell# | 224 | 1991-2000 | |
| 57 | Andre Dawson# | 222 | 1989-2000 | |
| 58 | Boze Berger | 220 | 1982-1997 | |
| 58 | Claudell Washington# | 220 | 1983-2000 | |
| 60 | Danny Gardella | 219 | 1980-1989 | |
| 61 | Austin Meadows | 218 | 1981-1993 | |
| 61 | AJ Pollock# | 218 | 1986-2000 | |
| 61 | Vern Stephens# | 218 | 1989-2000 | |
| 64 | Alex Avila# | 217 | 1985-2000 | |
| 65 | Billy Baldwin | 212 | 1980-1989 | |
| 65 | Eddie Miller | 212 | 1982-1997 | |
| 67 | Erubiel Durazo# | 208 | 1990-2000 | |
| 68 | Jim Lemon | 207 | 1982-1999 | |
| 69 | Bobby Estalella | 203 | 1984-1998 | |
| 70 | Ruben Rivera | 200 | 1982-1997 | |
| 71 | Cecil Fielder | 199 | 1985-1992 | |
| 72 | Marcus Giles# | 197 | 1987-2000 | |
| 72 | Jeff Kent# | 197 | 1989-2000 | |
| 72 | Ted Kluszewski# | 197 | 1996-2000 | |
| 75 | J.D. Drew | 196 | 1986-1993 | |
| 76 | Matt Kemp# | 195 | 1994-2000 | |
| 77 | Mel Ott | 193 | 1984-1995 | |
| 77 | Denny Sothern | 193 | 1982-1997 | |
| 79 | Delwyn Young | 191 | 1980-1990 | |
| 80 | Eric Karros | 190 | 1980-1990 | |
| 80 | Geronimo Pena# | 190 | 1985-2000 | |
| 80 | Joe Rudi | 190 | 1982-1991 | |
| 83 | Ivan Calderon# | 189 | 1985-2000 | |
| 84 | Willy Aybar# | 188 | 1987-2000 | |
| 84 | Carl Furillo | 188 | 1986-2000 | |
| 86 | Jurickson Profar | 187 | 1980-1997 | |
| 87 | Byron Browne# | 184 | 1992-2000 | |
| 87 | Les Moss | 184 | 1984-1999 | |
| 89 | Jack Rothrock# | 179 | 1994-2000 | |
| 89 | Hector Sanchez# | 179 | 1984-2000 | |
| 91 | Wil Cordero# | 178 | 1992-2000 | |
| 91 | Adam Jones# | 178 | 1990-2000 | |
| 93 | Bobby Dalbec | 177 | 1985-1995 | |
| 94 | Hank Aaron | 175 | 1980-1987 | |
| 94 | Cedric Mullins | 175 | 1983-1997 | |
| 96 | Hunter Pence# | 174 | 1993-2000 | |
| 96 | Bill Robinson | 174 | 1980-1989 | |
| 98 | Bruce Campbell# | 172 | 1985-1999 | |
| 99 | Roberto Clemente | 171 | 1980-1994 | |
| 100 | Desmond Jennings# | 170 | 1990-2000 |
