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| Second Basemen Single-Season Assists Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Assists | IP | Year | Career Leaderboard |
| 1. | Bill Regan | 717 | 1349.3 | 1931 | |
| 2. | Charlie Gehringer | 714 | 1381.3 | 1930 | |
| 3. | George Grantham | 680 | 1260.7 | 1932 | |
| 4. | Tony Lazzeri * | 667 | 1326.7 | 1936 | |
| 5. | Paul Molitor | 656 | 1312.3 | 1987 | |
| 6. | Max Bishop | 655 | 1255.3 | 1933 | |
| 7. | Bill Serena | 652 | 1274.7 | 1954 | |
| 8. | Greg Luzinski | 650 | 1335.3 | 1988 | |
| 9. | Max Bishop | 648 | 1325.0 | 1931 | |
| 10. | Bob Barrett | 646 | 1263.7 | 1931 | |
| 11. | Jerry Remy | 645 | 1328.7 | 1975 | |
| 12. | Lew Fonseca | 644 | 1309.3 | 1930 | |
| 13. | Alex Kampouris | 643 | 1284.7 | 1939 | |
| 14. | Cecil Travis | 642 | 1275.7 | 1942 | |
| 15. | Johnny Lucadello | 641 | 1271.7 | 1948 | |
| Greg Mulleavy | 641 | 1232.0 | 1939 | ||
| 17. | Jerry Terrell | 635 | 1206.3 | 1979 | |
| Rod Carew | 635 | 1320.7 | 1973 | ||
| Stan Hack | 635 | 1317.0 | 1938 | ||
| 20. | Eddie Stanky | 634 | 1366.3 | 1946 | |
| 21. | Joe Gordon | 632 | 1262.7 | 1942 | |
| 22. | Bill Serena | 630 | 1344.3 | 1951 | |
| 23. | Bill Serena | 627 | 1301.3 | 1953 | |
| 24. | Duane Kuiper | 626 | 1280.0 | 1979 | |
| 25. | Wally Kimmick | 625 | 1257.7 | 1931 | |
| 26. | Lou Whitaker | 624 | 1287.0 | 1979 | |
| Randy Reese | 624 | 1271.7 | 1930 | ||
| 28. | Heinie Mueller | 623 | 1232.7 | 1940 | |
| Lew Fonseca | 623 | 1287.7 | 1931 | ||
| 30. | Jake Flowers | 622 | 1282.0 | 1930 | |
| 31. | Rod Carew | 620 | 1353.7 | 1972 | |
| George Strickland | 620 | 1291.3 | 1956 | ||
| 33. | Doc Gautreau | 618 | 1215.3 | 1936 | |
| 34. | Jackie Robinson | 616 | 1327.7 | 1947 | |
| Frankie Crosetti | 616 | 1263.0 | 1936 | ||
| 36. | Bill Serena | 615 | 1298.3 | 1955 | |
| Tony Cuccinello | 615 | 1309.7 | 1942 | ||
| Lou Chiozza | 615 | 1277.7 | 1940 | ||
| Buddy Hassett | 615 | 1320.3 | 1937 | ||
| 40. | Juan Samuel | 614 | 1310.7 | 1985 | |
| Eddie Stanky | 614 | 1296.3 | 1944 | ||
| Alex Kampouris | 614 | 1282.3 | 1937 | ||
| 43. | Joe Gordon | 613 | 1285.7 | 1941 | |
| Tony Cuccinello | 613 | 1269.7 | 1941 | ||
| Alex Kampouris | 613 | 1309.0 | 1936 | ||
| 46. | Lou Whitaker | 612 | 1269.3 | 1981 | |
| Buddy Blattner * | 612 | 1268.3 | 1944 | ||
| Fresco Thompson | 612 | 1255.3 | 1934 | ||
| 49. | Eddie Stanky | 611 | 1359.3 | 1951 | |
| 50. | Juan Samuel | 609 | 1304.3 | 1984 | |
| Rob Andrews | 609 | 1309.7 | 1977 | ||
| Pee Wee Reese * | 609 | 1349.3 | 1954 | ||
| 53. | Darrell Evans | 607 | 1326.3 | 1973 | |
| Tony Lazzeri * | 607 | 1316.0 | 1930 | ||
| 55. | Grady Hatton | 606 | 1335.7 | 1952 | |
| 56. | Bill Mazeroski | 605 | 1214.0 | 1962 | |
| 57. | Tim Teufel | 604 | 1225.0 | 1987 | |
| Ron Oester | 604 | 1307.3 | 1982 | ||
| Willie Jones | 604 | 1300.3 | 1954 | ||
| 60. | Greg Luzinski | 603 | 1327.3 | 1986 | |
| 61. | Bobby Richardson | 602 | 1334.3 | 1969 | |
| Gil McDougald * | 602 | 1286.3 | 1963 | ||
| Gordon Slade | 602 | 1193.3 | 1937 | ||
| 64. | Max Bishop | 601 | 1290.0 | 1930 | |
| 65. | Ed Montague | 600 | 1315.7 | 1938 | |
| Fresco Thompson | 600 | 1242.3 | 1933 | ||
| 67. | Gene Stephens | 599 | 1273.0 | 1955 | |
| Willie Jones | 599 | 1318.7 | 1953 | ||
| Jackie Robinson | 599 | 1293.3 | 1946 | ||
| 70. | Roy Hartsfield | 598 | 1285.0 | 1952 | |
| Eddie Stanky | 598 | 1253.0 | 1945 | ||
| Alex Kampouris | 598 | 1290.3 | 1938 | ||
| 73. | Tony Phillips | 597 | 1366.3 | 1984 | |
| Roy Hartsfield | 597 | 1305.7 | 1956 | ||
| Lou Klein | 597 | 1284.0 | 1943 | ||
| 76. | Paul Molitor | 596 | 1277.7 | 1985 | |
| Dario Lodigiani | 596 | 1270.3 | 1939 | ||
| 78. | Tim Teufel | 595 | 1236.3 | 1983 | |
| George Strickland | 595 | 1338.3 | 1958 | ||
| Alvin Dark | 595 | 1320.0 | 1951 | ||
| Alex Kampouris | 595 | 1273.3 | 1943 | ||
| 82. | Don Buford | 594 | 1308.0 | 1963 | |
| Billy Cox | 594 | 1328.7 | 1954 | ||
| 84. | Sergio Ferrer | 593 | 1302.7 | 1981 | |
| Bobby Knoop | 593 | 1281.7 | 1973 | ||
| 86. | Max Bishop | 592 | 1171.3 | 1932 | |
| 87. | Randy Ready | 590 | 1279.0 | 1990 | |
| Dick Groat | 590 | 1285.3 | 1963 | ||
| Stan Hack | 590 | 1306.7 | 1943 | ||
| Buddy Myer | 590 | 1297.3 | 1938 | ||
| Doc Gautreau | 590 | 1195.0 | 1933 | ||
| 92. | Rick Renick | 589 | 1250.0 | 1975 | |
| Willie Jones | 589 | 1259.7 | 1957 | ||
| 94. | George Strickland | 588 | 1309.3 | 1957 | |
| 95. | Willie Randolph | 587 | 1234.7 | 1988 | |
| Sergio Ferrer | 587 | 1268.7 | 1982 | ||
| Jim Gilliam | 587 | 1292.0 | 1954 | ||
| Hughie Critz | 587 | 1246.0 | 1936 | ||
| 99. | Nelson Liriano | 586 | 1281.3 | 1990 | |
| Nelson Liriano | 586 | 1296.0 | 1989 | ||
| Johnny Hodapp | 586 | 1373.3 | 1936 | ||
| Billy Herman | 586 | 1244.0 | 1935 | ||
| 103. | Bobby Grich | 585 | 1273.0 | 1980 | |
| Leo Cardenas | 585 | 1280.3 | 1970 | ||
| Ron Santo | 585 | 1324.0 | 1962 | ||
| Eddie Lake | 585 | 1303.3 | 1945 | ||
| Billy Herman | 585 | 1216.3 | 1932 | ||
| 108. | Grady Hatton | 584 | 1277.7 | 1953 | |
| Bill Serena | 584 | 1337.7 | 1950 | ||
| Pee Wee Reese * | 584 | 1287.7 | 1945 | ||
| Eddie Lake | 584 | 1331.0 | 1943 | ||
| Freddy Spurgeon | 584 | 1251.7 | 1930 | ||
| 113. | George Kell | 582 | 1292.3 | 1951 | |
| Stan Hack | 582 | 1320.7 | 1942 | ||
| 115. | Lou Whitaker | 581 | 1327.7 | 1982 | |
| 116. | Jerry Terrell | 580 | 1156.3 | 1980 | |
| Joel Youngblood | 580 | 1299.0 | 1977 | ||
| Bobby Grich | 580 | 1285.3 | 1973 | ||
| 119. | Mike Schmidt | 579 | 1284.3 | 1973 | |
| Bobby Richardson | 579 | 1255.7 | 1965 | ||
| Lou Stringer | 579 | 1340.3 | 1949 | ||
| Alex Kampouris | 579 | 1280.7 | 1942 | ||
| George Grantham | 579 | 1135.0 | 1934 | ||
| 124. | Juan Samuel | 578 | 1306.0 | 1986 | |
| Lee Lacy | 578 | 1313.7 | 1981 | ||
| 126. | Robby Thompson | 577 | 1296.3 | 1989 | |
| Al Kozar | 577 | 1257.3 | 1950 | ||
| Tony Lazzeri * | 577 | 1218.7 | 1933 | ||
| Wally Kimmick | 577 | 1134.7 | 1932 | ||
| 130. | Roy Hartsfield | 576 | 1278.0 | 1951 | |
| 131. | Paul Molitor | 575 | 1286.3 | 1986 | |
| 132. | Terry Harmon | 574 | 1305.3 | 1979 | |
| Tony Lazzeri * | 574 | 1230.3 | 1931 | ||
| 134. | George Archie | 573 | 1285.0 | 1944 | |
| Bob Barrett | 573 | 1220.7 | 1932 | ||
| 136. | Johnny Ray | 572 | 1326.7 | 1983 | |
| Cookie Rojas | 572 | 1337.0 | 1973 | ||
| Al Kozar | 572 | 1297.0 | 1955 | ||
| Fresco Thompson | 572 | 1298.0 | 1931 | ||
| 140. | Bobby Grich | 571 | 1261.3 | 1983 | |
| Eddie Stanky | 571 | 1204.3 | 1943 | ||
| 142. | Mike Gates | 570 | 1208.0 | 1982 | |
| Bump Wills | 570 | 1334.3 | 1981 | ||
| Denny Doyle | 570 | 1266.3 | 1977 | ||
| Jim Gilliam | 570 | 1253.0 | 1953 | ||
| Frankie Crosetti | 570 | 1292.3 | 1938 | ||
| Mark Koenig | 570 | 1143.0 | 1932 | ||
| 148. | Pedro Garcia | 569 | 1299.7 | 1984 | |
| Lee Lacy | 569 | 1307.3 | 1977 | ||
| Lou Stringer | 569 | 1334.0 | 1950 | ||
| Max Bishop | 569 | 1203.3 | 1935 | ||
| 152. | Jose Baez | 568 | 1294.3 | 1983 | |
| Mike Schmidt | 568 | 1302.3 | 1975 | ||
| 154. | Mike Schmidt | 567 | 1238.0 | 1974 | |
| Alex Kampouris | 567 | 1266.7 | 1940 | ||
| Doc Gautreau | 567 | 1192.3 | 1932 | ||
| Doc Gautreau | 567 | 1270.7 | 1931 | ||
| Fresco Thompson | 567 | 1214.7 | 1930 | ||
| 159. | Tim Teufel | 566 | 1262.7 | 1984 | |
| Jerry Terrell | 566 | 1223.0 | 1978 | ||
| Ted Sizemore | 566 | 1178.3 | 1977 | ||
| Mike De La Hoz | 566 | 1273.0 | 1975 | ||
| Bobby Grich | 566 | 1259.0 | 1974 | ||
| Rod Carew | 566 | 1305.3 | 1970 | ||
| 165. | Spike Owen | 565 | 1316.0 | 1986 | |
| Stan Hack | 565 | 1272.3 | 1941 | ||
| Tony Lazzeri * | 565 | 1287.0 | 1937 | ||
| 168. | Willie Randolph | 563 | 1266.7 | 1989 | |
| Juan Samuel | 563 | 1313.0 | 1987 | ||
| Paul Molitor | 563 | 1274.0 | 1980 | ||
| Tom Heintzelman | 563 | 1241.3 | 1980 | ||
| Jim Gantner | 563 | 1250.0 | 1978 | ||
| Bobby Grich | 563 | 1294.3 | 1977 | ||
| Luis Olmo | 563 | 1277.3 | 1950 | ||
| 175. | Johnny Ray | 562 | 1314.3 | 1984 | |
| Bump Wills | 562 | 1291.4 | 1982 | ||
| Lee Lacy | 562 | 1285.3 | 1975 | ||
| Aaron Pointer | 562 | 1250.7 | 1966 | ||
| Jim Gilliam | 562 | 1324.7 | 1962 | ||
| Luis Olmo | 562 | 1280.3 | 1946 | ||
| Max Bishop | 562 | 1229.0 | 1934 | ||
| 182. | Wayne Causey | 561 | 1310.3 | 1968 | |
| Tony Lazzeri * | 561 | 1247.7 | 1932 | ||
| 184. | Tony Phillips | 560 | 1226.7 | 1983 | |
| Dick Howser | 560 | 1294.0 | 1962 | ||
| Chico Carrasquel | 560 | 1261.0 | 1962 | ||
| Buddy Blattner * | 560 | 1233.0 | 1945 | ||
| Frankie Crosetti | 560 | 1255.7 | 1937 | ||
| 189. | Robby Thompson | 559 | 1308.3 | 1987 | |
| Bump Wills | 559 | 1333.7 | 1984 | ||
| Paul Molitor | 559 | 1301.0 | 1984 | ||
| Bump Wills | 559 | 1348.7 | 1983 | ||
| Cookie Rojas | 559 | 1373.0 | 1972 | ||
| Roy Hartsfield | 559 | 1317.7 | 1958 | ||
| Bill Serena | 559 | 1113.0 | 1952 | ||
| Randy Reese | 559 | 1179.0 | 1932 | ||
| 197. | Roberto Alomar | 558 | 1268.7 | 1989 | |
| Jorge Orta | 558 | 1232.7 | 1979 | ||
| Tom Heintzelman | 558 | 1171.7 | 1977 | ||
| Tommy Thevenow | 558 | 1218.3 | 1932 | ||
| 201. | Jorge Orta | 557 | 1303.7 | 1980 | |
| Dick McAuliffe | 557 | 1234.7 | 1965 | ||
| Gil McDougald * | 557 | 1355.3 | 1961 | ||
| Joe Gordon | 557 | 1216.0 | 1944 | ||
| Charlie English | 557 | 1156.3 | 1935 | ||
| 206. | Jay Bell | 556 | 1294.7 | 1989 | |
| Gil McDougald * | 556 | 1247.3 | 1964 | ||
| Jim Finigan | 556 | 1267.7 | 1959 | ||
| 209. | Lee Lacy | 555 | 1268.0 | 1982 | |
| Lou Boudreau | 555 | 1261.0 | 1945 | ||
| Doc Gautreau | 555 | 1148.7 | 1934 | ||
| 212. | Tom Herr | 554 | 1276.7 | 1983 | |
| Bob Heise | 554 | 1180.3 | 1983 | ||
| Paul Molitor | 554 | 1325.3 | 1981 | ||
| Joe Gordon | 554 | 1170.0 | 1940 | ||
| Tony Lazzeri * | 554 | 1214.3 | 1934 | ||
| Hughie Critz | 554 | 1126.3 | 1934 | ||
| 218. | Tom Herr | 553 | 1283.0 | 1988 | |
| Bobby Grich | 553 | 1286.3 | 1981 | ||
| Stan Hack | 553 | 1291.3 | 1945 | ||
| 221. | Rod Carew | 552 | 1303.3 | 1968 | |
| Harvey Kuenn | 552 | 1341.0 | 1960 | ||
| Jerry Coleman | 552 | 1218.3 | 1951 | ||
| Lonny Frey | 552 | 1134.3 | 1942 | ||
| Lonny Frey | 552 | 1079.4 | 1941 | ||
| Alex Kampouris | 552 | 1260.3 | 1935 | ||
| Hughie Critz | 552 | 1237.0 | 1932 | ||
| Doc Gautreau | 552 | 1253.0 | 1930 | ||
| 229. | Tony Taylor | 551 | 1295.0 | 1969 | |
| Jim Gilliam | 551 | 1274.0 | 1961 | ||
| Pee Wee Reese * | 551 | 1333.7 | 1948 | ||
| 232. | Pete Mackanin | 550 | 1140.3 | 1982 | |
| Cookie Rojas | 550 | 1331.3 | 1969 | ||
| Lou Stringer | 550 | 1256.3 | 1951 | ||
| Dick Culler | 550 | 1238.3 | 1940 | ||
| 236. | Bump Wills | 549 | 1356.3 | 1980 | |
| Ron Dunn | 549 | 1112.0 | 1978 | ||
| Ted Sizemore | 549 | 1213.3 | 1975 | ||
| Jim Gilliam | 549 | 1287.7 | 1963 | ||
| Jackie Robinson | 549 | 1238.3 | 1945 | ||
| 241. | Roy Smalley | 548 | 1299.0 | 1986 | |
| Bobby Richardson | 548 | 1207.3 | 1966 | ||
| Stan Hack | 548 | 1257.0 | 1944 | ||
| Lonny Frey | 548 | 1177.7 | 1936 | ||
| 245. | Jerry Terrell | 547 | 1187.0 | 1981 | |
| Lou Whitaker | 547 | 1303.7 | 1980 | ||
| Miguel Dilone | 547 | 1251.7 | 1978 | ||
| Mike De La Hoz | 547 | 1168.7 | 1971 | ||
| Jose Pagan | 547 | 1295.7 | 1969 | ||
| Johnny Lucadello | 547 | 1257.0 | 1951 | ||
| Pee Wee Reese * | 547 | 1327.7 | 1944 | ||
| 252. | Rod Carew | 546 | 1260.3 | 1974 | |
| Bobby Knoop | 546 | 1206.3 | 1974 | ||
| Eddie Leon | 546 | 1231.0 | 1970 | ||
| Wayne Causey | 546 | 1248.7 | 1967 | ||
| Jim Finigan | 546 | 1320.3 | 1956 | ||
| Eddie Lake | 546 | 1252.3 | 1951 | ||
| Tony Lazzeri * | 546 | 1165.0 | 1935 | ||
| 259. | Jack Perconte | 545 | 1330.3 | 1984 | |
| Johnny Lucadello | 545 | 1068.0 | 1947 | ||
| Alex Kampouris | 545 | 1235.3 | 1945 | ||
| 262. | Mike Shannon | 544 | 1258.7 | 1974 | |
| Gil McDougald * | 544 | 1298.4 | 1962 | ||
| 264. | Tom Herr | 543 | 1263.3 | 1984 | |
| Bobby Grich | 543 | 1260.7 | 1979 | ||
| Chuck Harrison | 543 | 1243.0 | 1972 | ||
| Hank Thompson | 543 | 1249.3 | 1959 | ||
| Marv Olson | 543 | 1139.3 | 1935 | ||
| Charlie Gehringer | 543 | 1149.7 | 1932 | ||
| 270. | Jorge Orta | 542 | 1229.0 | 1987 | |
| Jorge Orta | 542 | 1256.7 | 1978 | ||
| Bobby Valentine | 542 | 1135.3 | 1975 | ||
| Eddie Lake | 542 | 1273.0 | 1947 | ||
| Alex Kampouris | 542 | 1209.0 | 1944 | ||
| Johnny Lucadello | 542 | 1246.7 | 1942 | ||
| Riggs Stephenson | 542 | 1262.0 | 1930 | ||
| 277. | Miguel Dilone | 541 | 1329.0 | 1979 | |
| Lee Handley | 541 | 1224.0 | 1947 | ||
| 279. | Bip Roberts | 540 | 1279.7 | 1989 | |
| Ted Sizemore | 540 | 1240.3 | 1971 | ||
| Dick McAuliffe | 540 | 1314.7 | 1970 | ||
| Jose Pagan | 540 | 1250.7 | 1962 | ||
| 283. | Robby Thompson | 539 | 1273.3 | 1990 | |
| Dick McAuliffe | 539 | 1290.3 | 1971 | ||
| Cookie Rojas | 539 | 1280.7 | 1967 | ||
| Jim Gilliam | 539 | 1258.3 | 1955 | ||
| Dick Bartell | 539 | 1076.3 | 1937 | ||
| 288. | Pedro Garcia | 538 | 1263.0 | 1983 | |
| 289. | Tom Herr | 537 | 1231.0 | 1990 | |
| Tim Teufel | 537 | 1209.0 | 1988 | ||
| Tom Herr | 537 | 1266.3 | 1987 | ||
| Steve Sax | 537 | 1278.0 | 1985 | ||
| Rod Carew | 537 | 1300.7 | 1971 | ||
| Pete Runnels | 537 | 1305.0 | 1958 | ||
| Hank Thompson | 537 | 1282.0 | 1955 | ||
| Billy Herman | 537 | 1190.0 | 1933 | ||
| 297. | Glenn Hubbard | 536 | 1213.7 | 1981 | |
| Paul Molitor | 536 | 1250.7 | 1979 | ||
| Alan Bannister | 536 | 1160.3 | 1978 | ||
| Roy Hartsfield | 536 | 1174.7 | 1950 |
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