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| Second Basemen Career Slugging Pct Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Slugging Pct | PA | Years | Single Season Leaderboard |
| 1. | Gil McDougald * | .5346 | 8973 | 1951-1965 | |
| 2. | Grady Hatton | .4849 | 5328 | 1946-1953 | |
| 3. | Tony Lazzeri * | .4789 | 7117 | 1930-1941 | |
| 4. | Paul Molitor | .4702 | 7915 | 1978-1990 | |
| 5. | Don Demeter | .4595 | 7229 | 1958-1971 | |
| 6. | Hank Thompson | .4521 | 8521 | 1947-1962 | |
| 7. | Lou Whitaker | .4440 | 7303 | 1978-1990 | |
| 8. | Joe Gordon | .4370 | 3989 | 1938-1950 | |
| 9. | Willie Horton | .4288 | 8507 | 1965-1980 | |
| 10. | Greg Luzinski | .4261 | 10636 | 1971-1988 | |
| 11. | George Grantham | .4259 | 3075 | 1930-1936 | |
| 12. | Johnny Hodapp | .4214 | 5384 | 1930-1941 | |
| 13. | Joe Morgan | .4204 | 11796 | 1963-1982 | |
| 14. | Gary Geiger | .4201 | 7277 | 1960-1973 | |
| 15. | Lee Walls | .4181 | 8031 | 1955-1969 | |
| 16. | Max Bishop | .4172 | 4901 | 1930-1938 | |
| 17. | Stan Hack | .4147 | 9770 | 1933-1947 | |
| 18. | Pee Wee Reese * | .4144 | 10850 | 1940-1956 | |
| 19. | Bump Wills | .4131 | 7130 | 1977-1988 | |
| 20. | Billy Cox | .4107 | 7479 | 1941-1957 | |
| 21. | Jorge Orta | .4103 | 7336 | 1976-1988 | |
| 22. | Lou Stringer | .4099 | 6251 | 1941-1954 | |
| 23. | Rod Carew | .4072 | 9409 | 1967-1983 | |
| 24. | Jerry Standaert | .4058 | 3697 | 1930-1938 | |
| 25. | Bobby Avila | .4057 | 4265 | 1949-1960 | |
| 26. | Rance Mulliniks | .4043 | 7767 | 1978-1990 | |
| 27. | Ryne Sandberg | .4035 | 5379 | 1981-1990 | |
| 28. | Jim Davenport | .4019 | 3359 | 1958-1968 | |
| 29. | Tom Herr | .4000 | 6147 | 1981-1990 | |
| 30. | Jim Bucher | .3990 | 5654 | 1936-1949 | |
| 31. | Sherry Robertson | .3973 | 5770 | 1942-1955 | |
| 32. | Alex Kampouris | .3967 | 8618 | 1934-1949 | |
| 33. | Cecil Travis | .3956 | 7099 | 1934-1948 | |
| 34. | Dion James | .3951 | 3016 | 1984-1990 | |
| 35. | Pedro Garcia | .3938 | 5561 | 1975-1986 | |
| 36. | Mickey Rivers | .3925 | 4843 | 1973-1982 | |
| 37. | Charlie Gehringer | .3923 | 4091 | 1930-1939 | |
| 38. | Billy Johnson | .3894 | 5364 | 1943-1957 | |
| 39. | Jim Lefebvre | .3887 | 6564 | 1966-1978 | |
| 40. | Johnny Goryl | .3881 | 4973 | 1960-1970 | |
| 41. | Johnny Lucadello | .3871 | 6957 | 1940-1954 | |
| 42. | Lee Lacy | .3864 | 7483 | 1972-1986 | |
| 43. | Nelson Mathews | .3863 | 4788 | 1964-1974 | |
| 44. | Bobby Grich | .3853 | 7379 | 1973-1985 | |
| 45. | Hughie Critz | .3852 | 4335 | 1930-1937 | |
| 46. | Bill Cissell | .3838 | 3704 | 1930-1941 | |
| 47. | Ken Boswell | .3833 | 5015 | 1971-1981 | |
| 48. | Fresco Thompson | .3828 | 3284 | 1930-1937 | |
| 49. | Dutch Meyer | .3804 | 5288 | 1941-1952 | |
| 50. | Jim Gilliam | .3799 | 6930 | 1953-1963 | |
| 51. | Paul Schaal | .3797 | 6529 | 1965-1979 | |
| 52. | Pete Runnels | .3779 | 7114 | 1952-1964 | |
| 53. | Billy Herman | .3777 | 7161 | 1932-1945 | |
| 54. | Mark Koenig | .3776 | 5408 | 1930-1941 | |
| 55. | Bama Rowell | .3757 | 3696 | 1941-1953 | |
| 56. | Ted Sizemore | .3756 | 5889 | 1970-1981 | |
| 57. | Roy Hartsfield | .3755 | 4471 | 1950-1958 | |
| 58. | Bernie James | .3751 | 3697 | 1930-1941 | |
| 59. | Juan Samuel | .3734 | 4225 | 1983-1990 | |
| 60. | Joel Youngblood | .3728 | 4993 | 1977-1986 | |
| 61. | Lonny Frey | .3722 | 3718 | 1935-1946 | |
| 62. | Damaso Garcia | .3703 | 3357 | 1980-1990 | |
| 63. | Marty Martinez | .3702 | 6264 | 1962-1978 | |
| 64. | Charley Smith | .3700 | 3908 | 1961-1972 | |
| 65. | Lenn Sakata | .3698 | 3345 | 1983-1990 | |
| 66. | Joe Caffie | .3680 | 4441 | 1957-1969 | |
| 67. | Kiko Garcia | .3679 | 5644 | 1979-1990 | |
| 68. | Billy Myers | .3669 | 4858 | 1935-1949 | |
| 69. | Bernie Allen | .3669 | 4142 | 1962-1972 | |
| 70. | Tito Fuentes | .3655 | 5415 | 1966-1981 | |
| 71. | Bobby Reeves | .3652 | 4861 | 1930-1939 | |
| 72. | Solly Hemus | .3648 | 5849 | 1949-1960 | |
| 73. | Felix Millan | .3634 | 5199 | 1968-1980 | |
| 74. | Tommy Glaviano | .3632 | 6901 | 1951-1962 | |
| 75. | Rick Manning | .3628 | 6261 | 1975-1988 | |
| 76. | Red Schoendienst | .3624 | 3142 | 1947-1959 | |
| 77. | Doc Gautreau | .3607 | 4782 | 1930-1938 | |
| 78. | Don Buddin | .3601 | 4566 | 1958-1971 | |
| 79. | Eddie Stanky | .3593 | 5930 | 1943-1953 | |
| 80. | Stu Martin | .3588 | 3608 | 1937-1947 | |
| 81. | Don Blasingame | .3585 | 7457 | 1956-1970 | |
| 82. | Gene Stephens | .3580 | 6242 | 1955-1969 | |
| 83. | Chico Carrasquel | .3566 | 6237 | 1951-1964 | |
| 84. | Rob Andrews | .3564 | 4285 | 1976-1987 | |
| 85. | Davey Lopes | .3563 | 3628 | 1972-1978 | |
| 86. | Derrel Thomas | .3557 | 3085 | 1977-1983 | |
| 87. | Frank Bolling | .3547 | 3545 | 1957-1968 | |
| 88. | Leo Cardenas | .3539 | 6972 | 1961-1977 | |
| 89. | Jack Perconte | .3515 | 5399 | 1980-1990 | |
| 90. | Rudy Meoli | .3505 | 3268 | 1977-1989 | |
| 91. | Mike De La Hoz | .3498 | 6019 | 1962-1976 | |
| 92. | Ron Theobald | .3491 | 3734 | 1971-1978 | |
| 93. | Bert Campaneris | .3413 | 4375 | 1965-1975 | |
| 94. | Terry Harmon | .3410 | 4749 | 1970-1979 | |
| 95. | Tim Teufel | .3404 | 3207 | 1983-1990 | |
| 96. | Chuck Schilling | .3366 | 6580 | 1962-1974 | |
| 97. | Taylor Duncan | .3335 | 5305 | 1978-1989 | |
| 98. | Al Kozar | .3320 | 3047 | 1949-1955 | |
| 99. | Tom Upton | .3312 | 5226 | 1953-1964 | |
| 100. | George Strickland | .3293 | 4271 | 1954-1962 | |
| 101. | Randy Ready | .3289 | 3950 | 1983-1990 | |
| 102. | Rodney Scott | .3249 | 6432 | 1977-1990 | |
| 103. | Jerry Terrell | .3222 | 4782 | 1973-1982 | |
| 104. | Paul Runge | .3007 | 3021 | 1985-1990 | |
| 105. | Rob Ellis | .2763 | 4143 | 1975-1986 |
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